<生产厂家价格>

氰乙酰胺

氰乙酰胺用途

【用途一】
用作医药、染料及电镀液中间体
【用途二】
用机合成原料，用于合成丙二腈和电镀液，还用于药物氨苯喋啶、氨蝶呤的合成。

氰乙酰胺名称

[ CAS 号 ]:
107-91-5

[ 中文名 ]:
氰乙酰胺

[ 英文名 ]:
2-Cyanoacetamide

[中文别名 ]:

[英文别名 ]:

cyanoacetic acid amide
Cyanoiminoacetic acid
Malonamide nitrile
Cyanomethylformamide
Cyanacetamide
EINECS 203-531-8
2-cyano-acetamide
Acetamide,2-cyano
2-Cyanoacetamide
cyanoacetoamide

氰乙酰胺物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
246.1±42.0 °C at 760 mmHg

[ 熔点 ]:
119-121 °C(lit.)

[ 分子式 ]:
C₃H₄N₂O

[ 分子量 ]:
84.077

[ 闪点 ]:
102.6±27.9 °C

[ 精确质量 ]:
84.032364

[ PSA ]:
66.88000

[ LogP ]:
-1.44

[ 外观性状 ]:
白色至淡奶油色结晶粉末

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.504

[ 储存条件 ]:
室温

[ 水溶解性 ]:
soluble

氰乙酰胺MSDS

氰乙酰胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AB5950000

CHEMICAL NAME :: Acetamide, 2-cyano-

CAS REGISTRY NUMBER :: 107-91-5

BEILSTEIN REFERENCE NO. :: 0878221

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C3-H4-N2-O

MOLECULAR WEIGHT :: 84.09

WISWESSER LINE NOTATION :: ZV1CN

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1680 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KHZDAN Khigiena i Zdraveopazvane. Hygiene and Sanitation. (Hemus, Blvd. Russki 6, Sofia, Bulgaria) V.9- 1966- Volume(issue)/page/year: 9,50,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 1155 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - muscle contraction or spasticity Gastrointestinal - nausea or vomiting

REFERENCE :: MELAAD Medicina del Lavoro. Industrial Medicine. (Via S. Barnaba, 8, 20122 Milan, Italy) V.16- 1925- Volume(issue)/page/year: 47,192,1956 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1982 No. of Facilities: 3 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 870 (estimated) No. of Female Employees: 45 (estimated)

氰乙酰胺安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R20/21/22

[ 安全声明 (欧洲) ]:
S22-S26-S28A

[ 危险品运输编码 ]:
UN 3439 6.1/PG 3

[ WGK德国 ]:
2

[ RTECS号 ]:
AB5950000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2926909090

氰乙酰胺合成路线

氰乙酰胺上下游产品

氰乙酰胺上游产品

氰乙酰胺下游产品

氰乙酰胺制备

可由氰乙酸乙酯与氨作用制得。将氰乙酸乙酯冷却至200℃以下，加入浓氨水进行反应，得混合物由浊变清，在冷水中冷却20分钟后析出沉淀，经过滤、甩干后得粗品，然后将氰乙酰胺粗品加入沸腾的乙醇中，待其溶解后，再加入少量活性炭脱色精制，过滤，滤液冷却析出沉淀，经甩干后于80-100℃下干燥制得氰乙酰胺精品。

氰乙酰胺海关

[ 海关编码 ]: 2926909090

[ 中文概述 ]:
2926909090 其他腈基化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

氰乙酰胺文献

Diversity-oriented, one-pot, multi-component synthesis of substituted uracil derivatives.

Mol. Divers. 15(1) , 263-7, (2011)

With the emergence of high throughput screening of bioactive molecules, there is constant need for the development of new strategies for diversity-oriented synthesis. We describe here a novel one-pot ...

Controlled synthesis of Fe3O4/ZIF-8 nanoparticles for magnetically separable nanocatalysts.

Chemistry 21(18) , 6879-87, (2015)

Fe3O4/ZIF-8 nanoparticles were synthesized through a room-temperature reaction between 2-methylimidazolate and zinc nitrate in the presence of Fe3O4 nanocrystals. The particle size, surface charge, an...

Acylation of heteroaromatic amines: facile and efficient synthesis of a new class of 1,2,3-triazolo[4,5-b]pyridine and pyrazolo[4,3-b]pyridine derivatives.

Molecules 16(5) , 3723-39, (2011)

1,2,3-Triazolo[4,5-b]pyridines and pyrazolo[4,3-b]pyridines can be readily prepared via cyanoacetylation reactions of 5-amino-1,2,3-triazoles 1a,b and 4-amino- pyrazole 2 followed by subsequent cycliz...

更多文献