甲基帕罗西汀

甲基帕罗西汀用途

N-methyl Paroxetine is a derivative of the selective serotonin reuptake inhibitor (SSRI) antidepressant paroxetine that inhibits [3H]paroxetine binding to rat cortical membranes. It inhibits serotonin (5-HT) uptake in rat brain synaptosomes and has been used as a precursor in the synthesis of paroxetine.

甲基帕罗西汀名称

[ CAS 号 ]:
110429-36-2

[ 中文名 ]:
N-甲基帕罗西汀

[ 英文名 ]:
N-Methylparoxetine

[中文别名 ]:

[英文别名 ]:

Paroxetine Related Compound F
MFCD03788781
N-Methyl Paroxetine
Paroxetine Impurity 9

甲基帕罗西汀物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
443.7±45.0 °C at 760 mmHg

[ 熔点 ]:
111 °C

[ 分子式 ]:
C₂₀H₂₂FNO₃

[ 分子量 ]:
343.392

[ 闪点 ]:
222.1±28.7 °C

[ 精确质量 ]:
343.158386

[ PSA ]:
30.93000

[ LogP ]:
3.91

[ 外观性状 ]:
固体;White to Almost white powder to crystal

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.562

[ 储存条件 ]:
Hygroscopic, -20°C Freezer, Under Inert Atmosphere

甲基帕罗西汀MSDS

详细MSDS(安全技术说明书)

甲基帕罗西汀安全信息

[ 符号 ]:

GHS06, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301-H410

[ 警示性声明 ]:
P273-P301 + P310-P501

[ 危害码 (欧洲) ]:
T,N

[ 风险声明 (欧洲) ]:
25-50/53

[ 安全声明 (欧洲) ]:
45-60-61

[ 危险品运输编码 ]:
UN 2811 6.1 / PGIII

[ 危险类别 ]:
6.1

甲基帕罗西汀合成路线

详细合成路线

甲基帕罗西汀上下游产品

甲基帕罗西汀上游产品

甲基帕罗西汀下游产品

甲基帕罗西汀文献

Depletion of selective serotonin reuptake inhibitors during sewage sludge composting.

Waste Manag. 29(11) , 2808-15, (2009)

Sewage and sewage sludge is known to contain pharmaceuticals, and since sewage sludge is often used as fertilizer within agriculture, the reduction of the selective serotonin reuptake inhibitors (SSRI...

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