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7-乙氧基-4-(三氟甲基)香豆素

7-乙氧基-4-(三氟甲基)香豆素用途

7-乙氧基-4-三氟甲基香豆素是细胞色素P450超家族各种酶的荧光底物[1]

7-乙氧基-4-(三氟甲基)香豆素名称

[ CAS 号 ]:
115453-82-2

[ 中文名 ]:
7-乙氧基-4-(三氟甲基)香豆素

[ 英文名 ]:
7-Ethoxy-4-(trifluoromethyl)coumarin

[英文别名 ]:

2H-1-Benzopyran-2-one,7-ethoxy-4-(trifluoromethyl)
7-Ethoxy-4-(trifluoromethyl)coumarin
Ethyl 4-(trifluoromethyl)umbelliferyl ether
7-Ethoxy-4-trifluoromethylcoumarin
Etfc cpd

7-乙氧基-4-(三氟甲基)香豆素生物活性

[ 描述 ]:

7-乙氧基-4-三氟甲基香豆素是细胞色素P450超家族各种酶的荧光底物[1]

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Morse MA, et al. High-performance liquid chromatographic method for measurement of cytochrome P450-mediated metabolism of 7-ethoxy-4-trifluoromethylcoumarin. J Chromatogr B Biomed Sci Appl. 1998 Apr 24;708(1-2):290-3.

7-乙氧基-4-(三氟甲基)香豆素物理化学性质

[ 密度 ]:
1.368 g/cm3

[ 沸点 ]:
303.1ºC at 760 mmHg

[ 分子式 ]:
C₁₂H₉F₃O₃

[ 分子量 ]:
258.19300

[ 闪点 ]:
132.7ºC

[ 精确质量 ]:
258.05000

[ PSA ]:
39.44000

[ LogP ]:
3.21050

[ 外观性状 ]:
白色粉末

[ 蒸汽压 ]:
0.000952mmHg at 25°C

[ 折射率 ]:
1.503

[ 储存条件 ]:
20°C

7-乙氧基-4-(三氟甲基)香豆素MSDS

详细MSDS(安全技术说明书)

7-乙氧基-4-(三氟甲基)香豆素安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 安全声明 (欧洲) ]:
22-24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2932209090

7-乙氧基-4-(三氟甲基)香豆素海关

[ 海关编码 ]: 2932209090

[ 中文概述 ]:
2932209090. 其他内酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

7-乙氧基-4-(三氟甲基)香豆素文献

HepG2 cells as an in vitro model for evaluation of cytochrome P450 induction by xenobiotics.

Arch. Pharm. Res. 38 , 691-704, (2015)

Although various in vitro assays have been developed to evaluate the cytochrome P450 (CYP)-inducing potential of drug candidates, there is a continuing need for the development of a reliable model in ...

Environmentally persistent free radical-containing particulate matter competitively inhibits metabolism by cytochrome P450 1A2.

Toxicol. Appl. Pharmacol. 289 , 223-30, (2015)

Combustion processes generate different types of particulate matter (PM) that can have deleterious effects on the pulmonary and cardiovascular systems. Environmentally persistent free radicals (EPFRs)...

Inhibition of cytochrome P450 2B4 by environmentally persistent free radical-containing particulate matter.

Biochem. Pharmacol. 95 , 126-32, (2015)

Combustion processes generate particulate matter (PM) that can affect human health. The presence of redox-active metals and aromatic hydrocarbons in the post-combustion regions results in the formatio...

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