二硫化二苯并噻唑

二硫化二苯并噻唑用途

【用途一】
用作天然胶、合成胶、再生胶的通用型促进剂，主要用于制造轮胎、内胎、胶带、胶鞋和一般工业制品
【用途二】
噻唑类硫化促进剂。可用于天然橡胶、合成橡胶和再生胶，用途与促进剂M基本相似，但硫化临界温度较高（130℃）。是目前常用的硫化促进剂之一，广泛用于轮胎、软管、橡胶垫、防水布、艳色的橡胶帛品、胶管、电线、电缆、胶鞋等非食品应用的橡胶制品。该品毒性小，但能刺激粘膜和皮肤。

二硫化二苯并噻唑名称

[ CAS 号 ]:
120-78-5

[ 中文名 ]:
二硫化二苯并噻唑

[ 英文名 ]:
2,2'-Dithiobis(benzothiazole)

[中文别名 ]:

[英文别名 ]:

2,2'-Dithiobis(benzothiazole)
2,2'-Disulfanediylbis(1,3-benzothiazol)
Mercaptobenztiazyl Ether
Perkacit MBTS
2,2'-Disulfanediylbis(1,3-benzothiazole)
Benzothiazol-2-yl disulfide
2,2-Dithiobisbenzothiazole
EINECS 204-424-9
2,2'-Dibenzothiazyl disulfide
2,2'-Dithiobis[benzothiazole]

二硫化二苯并噻唑物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
532.5±33.0 °C at 760 mmHg

[ 熔点 ]:
177-180 °C(lit.)

[ 分子式 ]:
C₁₄H₈N₂S₄

[ 分子量 ]:
332.487

[ 闪点 ]:
275.8±25.4 °C

[ 精确质量 ]:
331.957031

[ PSA ]:
132.86000

[ LogP ]:
7.04

[ 外观性状 ]:
黄色非晶形的粉末

[ 蒸汽压 ]:
0.0±1.4 mmHg at 25°C

[ 折射率 ]:
1.849

[ 储存条件 ]:
通风低温干燥

[ 水溶解性 ]:
<0.01 g/100 mL at 21 ºC

二硫化二苯并噻唑MSDS

二硫化二苯并噻唑毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DL4550000

CHEMICAL NAME :: Benzothiazole, 2,2'-dithiobis-

CAS REGISTRY NUMBER :: 120-78-5

BEILSTEIN REFERENCE NO. :: 0285796

LAST UPDATED :: 199804

DATA ITEMS CITED :: 18

MOLECULAR FORMULA :: C14-H8-N2-S4

MOLECULAR WEIGHT :: 332.48

WISWESSER LINE NOTATION :: T56 BN DSJ CSS- CT56 BN DSJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >12 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >7940 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 9100 mg/kg/13W-I

TOXIC EFFECTS :: Liver - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 172 gm/kg/78W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Blood - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

DOSE :: 400 mg/kg

SEX/DURATION :: female 4-11 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

DOSE :: 400 mg/kg

SEX/DURATION :: female 4-11 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetal death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

DOSE :: 800 mg/kg

SEX/DURATION :: male 2 day(s) pre-mating female 2 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth) Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

DOSE :: 800 mg/kg

SEX/DURATION :: male 2 day(s) pre-mating female 2 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetal death

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 15 mg/L

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 5,193,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84830 No. of Facilities: 897 (estimated) No. of Industries: 12 No. of Occupations: 28 No. of Employees: 11180 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84830 No. of Facilities: 1533 (estimated) No. of Industries: 19 No. of Occupations: 42 No. of Employees: 50590 (estimated) No. of Female Employees: 11091 (estimated)

二硫化二苯并噻唑安全信息

[ 符号 ]:

GHS07, GHS09

[ 信号词 ]:
Warning

[ 危害声明 ]:
H317-H410

[ 补充危害声明 ]:
Contact with acids liberates toxic gas.

[ 警示性声明 ]:
P273-P280-P501

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R31;R43;R50/53

[ 安全声明 (欧洲) ]:
S36/37-S60-S61

[ 危险品运输编码 ]:
UN 3077 9/PG 3

[ WGK德国 ]:
2

[ RTECS号 ]:
DL4550000

[ 危险类别 ]:
9.0

[ 海关编码 ]:
2934200090

二硫化二苯并噻唑合成路线

二硫化二苯并噻唑上下游产品

二硫化二苯并噻唑上游产品

二硫化二苯并噻唑下游产品

二硫化二苯并噻唑制备

将2-巯基苯并噻唑（参见促进剂M）和亚硝酸钠加入气相鼓泡塔内，滴加10%的硫酸溶液，并鼓入空气。控制反应温度在60℃左右。硫酸滴加完后，继续鼓入空气，温度仍保持60℃，直至反应完全。
生成的促进剂DM不溶于水，在料液中呈固体微粒。经过滤、水洗、离心脱水、干燥、粉碎、筛析、包装，即得成品。

二硫化二苯并噻唑海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

二硫化二苯并噻唑文献

Solid state differentiation of plasma thiols using a centrifugally activated mercaptobenzothiazole disulfide exchange indicator.

Chem. Commun. (Camb.) (6) , 592-4, (2007)

The solid state interaction of mono and macromolecular thiols at a disulfide heterocycle is shown to provide a versatile pathway for their speciation.

A wood preservative metabolite in river water.

Environ. Sci. Pollut. Res. Int. 12(1) , 8-9, (2005)

A previously unknown pollutant in river water was identified to be 2-mercaptobenzothiazole (2-MBT) by interpretation and simulation of its GC/LRMS spectrum. Further GC/HRMS measurement of the isotope ...

Allergic contact dermatitis from mercapto compounds.

Dermatitis 17(2) , 56-70, (2006)

Despite being well-known allergens, mercaptobenzothiazole and its derivatives continue to be widely used in natural and synthetic rubber, in the mining industry, and in a variety of nonrubber products...

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