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草灭畏

草灭畏用途

Chloramben (3-Amino-2,5-dichlorobenzoic acid) 是一种出苗前除草剂,用于抑制一年生草和阔叶杂草的幼苗的生长。

草灭畏名称

[ CAS 号 ]:
133-90-4

[ 中文名 ]:
草灭畏

[ 英文名 ]:
chloramben

[中文别名 ]:

[英文别名 ]:

Amiben
EINECS 205-123-5
ZR BG EG CVQ
3-Amino-2,5-dichlorobenzoic acid
chloramben
MFCD00065093
Benzoic acid, 3-amino-2,5-dichloro-

草灭畏生物活性

[ 描述 ]:

Chloramben (3-Amino-2,5-dichlorobenzoic acid) 是一种出苗前除草剂,用于抑制一年生草和阔叶杂草的幼苗的生长。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Thiam A, et al. On the performance of electrocatalytic anodes for photoelectro-Fenton treatment of synthetic solutions and real water spiked with the herbicide chloramben. J Environ Manage. 2018 Oct 15;224:340-349.

草灭畏物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
373.2±42.0 °C at 760 mmHg

[ 熔点 ]:
200 °C

[ 分子式 ]:
C₇H₅Cl₂NO₂

[ 分子量 ]:
206.026

[ 闪点 ]:
179.5±27.9 °C

[ 精确质量 ]:
204.969727

[ PSA ]:
63.32000

[ LogP ]:
2.52

[ 外观性状 ]:
紫白色粉末或淡紫色固体

[ 蒸汽压 ]:
0.0±0.9 mmHg at 25°C

[ 折射率 ]:
1.658

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运

[ 水溶解性 ]:
700 mg/L (25 ºC)

草灭畏MSDS

草灭畏毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DG1925000

CHEMICAL NAME :: Benzoic acid, 3-amino-2,5-dichloro-

CAS REGISTRY NUMBER :: 133-90-4

LAST UPDATED :: 199701

DATA ITEMS CITED :: 15

MOLECULAR FORMULA :: C7-H5-Cl2-N-O2

MOLECULAR WEIGHT :: 206.03

WISWESSER LINE NOTATION :: ZR BG EG CVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >2200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3725 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 3136 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 364 mg/kg/52W-I

TOXIC EFFECTS :: Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other transferases Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 672 gm/kg/80W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1344 gm/kg/80W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors

TYPE OF TEST :: Cytogenetic analysis

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 234 mg/kg

REFERENCE :: CARYAB Caryologia. (Via G. LaPira 4, 50121 Florence, Italy) V.1- 1948- Volume(issue)/page/year: 33,527,1980

草灭畏安全信息

[ 符号 ]:

GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H315-H319-H335-H350

[ 警示性声明 ]:
P201-P261-P305 + P351 + P338-P308 + P313

[ 个人防护装备 ]:
Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T:Toxic;Xn:Harmful;

[ 风险声明 (欧洲) ]:
R36/37/38;R40;R45

[ 安全声明 (欧洲) ]:
S53-S22-S26-S36/37/39-S45

[ 危险品运输编码 ]:
UN 3077 9/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
DG1925000

[ 海关编码 ]:
2922499911

草灭畏合成路线

草灭畏上下游产品

草灭畏上游产品

草灭畏下游产品

草灭畏制备

【方法一】
由对二氯苯经多聚甲醛氯甲基化、高锰酸钾氧化、硝酸硝化、锡粒还原而得。

草灭畏海关

[ 海关编码 ]: 2922499911

[ 中文概述 ]:
2922499911 草灭畏。监管条件:ABS(入境货物通关单,出境货物通关单,进出口农药登记证明)。增值税率:17.0%。退税率:9.0%。最低关税:6.5%。普通关税:30.0%

[ Summary ]:
2922499911 3-amino-2,5-dichlorobenzoic acid。supervision conditions:ABs(certificate of inspection for goods inward,certificate of inspection for goods outward,import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

草灭畏文献

Development of QSAR models for predicting hepatocarcinogenic toxicity of chemicals.

Eur. J. Med. Chem. 44 , 3658-64, (2009)

A dataset comprising 55 chemicals with hepatocarcinogenic potency indices was collected from the Carcinogenic Potency Database with the aim of developing QSAR models enabling prediction of the above u...

Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

J. Med. Chem. 51 , 6740-51, (2008)

The work provides a new model for the prediction of the MAO-A and -B inhibitor activity by the use of combined complex networks and QSAR methodologies. On the basis of the obtained model, we prepared ...

[Methods of controlling the harmful substance content in the air of a work area in amiben manufacture].

Gig. Tr. Prof. Zabol. (10) , 50-1, (1980)

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草灭畏