Pyridine,3-(3,3-diethyl-1-triazen-1-yl)-

Pyridine,3-(3,3-diethyl-1-triazen-1-yl)-名称

[ CAS 号 ]:
21600-43-1

[ 英文名 ]:
Pyridine,3-(3,3-diethyl-1-triazen-1-yl)-

[英文别名 ]:

Pyridine,3-(3,3-diethyl-1-triazen-1-yl)-物理化学性质

[ 密度 ]:
1.03g/cm3

[ 沸点 ]:
260.4ºC at 760mmHg

[ 分子式 ]:
C9H14N4

[ 分子量 ]:
178.23400

[ 闪点 ]:
111.3ºC

[ 精确质量 ]:
178.12200

[ PSA ]:
40.85000

[ LogP ]:
2.42210

[ 蒸汽压 ]:
0.0123mmHg at 25°C

[ 折射率 ]:
1.542

Pyridine,3-(3,3-diethyl-1-triazen-1-yl)-毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XY0495000
CHEMICAL NAME :
Triazene, 3,3-diethyl-1-(m-pyridyl)-
CAS REGISTRY NUMBER :
21600-43-1
LAST UPDATED :
199709
DATA ITEMS CITED :
15
MOLECULAR FORMULA :
C9-H14-N4
MOLECULAR WEIGHT :
178.27
WISWESSER LINE NOTATION :
T6NJ CNUNN2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
210 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - tremor Liver - fatty liver degeneration
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
210 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
660 mg/kg/73W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Brain and Coverings - tumors Cardiac - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg/50W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Blood - leukemia Skin and Appendages - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
55 mg/kg female 15 day(s) after conception
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Brain and Coverings - tumors
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
50 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Peripheral Nerve and Sensation - peripheral nerve tumors Skin and Appendages - tumors
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
60 mg/kg
SEX/DURATION :
female 10 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death Reproductive - Specific Developmental Abnormalities - eye/ear
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
DOSE :
167 mg/kg
SEX/DURATION :
female 15 day(s) after conception
TOXIC EFFECTS :
Reproductive - Effects on Embryo or Fetus - fetal death
TYPE OF TEST :
Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
100 mg/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 88,197,1981 *** REVIEWS *** TOXICOLOGY REVIEW 32XPAD "Teratology," Berry, C.L., and D.E. Poswillo, eds., New York, Springer, 1975 Volume(issue)/page/year: -,49,1975

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