2-[4-[[3-(acetyl-ethyl-amino)-2,4,6-triiodo-benzoyl]amino]phenyl]acetic acid

名称

[ CAS 号 ]:
22708-43-6

[ 英文名 ]:
2-[4-[[3-(acetyl-ethyl-amino)-2,4,6-triiodo-benzoyl]amino]phenyl]acetic acid

[英文别名 ]:

Patamostat mesylate
Patamostat mesilate

物理化学性质

[ 密度 ]:
2.175g/cm3

[ 沸点 ]:
669ºC at 760mmHg

[ 分子式 ]:
C₁₉H₁₇I₃N₂O₄

[ 分子量 ]:
718.06300

[ 精确质量 ]:
717.83200

[ PSA ]:
86.71000

[ LogP ]:
4.82560

[ 蒸汽压 ]:
8.24E-19mmHg at 25°C

[ 折射率 ]:
1.748

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AH3731300

CHEMICAL NAME :: Acetic acid, (p-(3-(N-ethylacetamido)-2,4,6-triiodobenzamido)pheny l)-

CAS REGISTRY NUMBER :: 22708-43-6

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C19-H17-I3-N2-O4

MOLECULAR WEIGHT :: 718.08

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >10 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HCACAV Helvetica Chimica Acta. (Verlag Helvetica Chimica Acta, Postfach, CH-4002 Basel, Switzerland) V.1- 1918- Volume(issue)/page/year: 52,1339,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 920 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: HCACAV Helvetica Chimica Acta. (Verlag Helvetica Chimica Acta, Postfach, CH-4002 Basel, Switzerland) V.1- 1918- Volume(issue)/page/year: 52,1339,1969

安全信息

[ 海关编码 ]:
2924299090

海关

[ 海关编码 ]: 2924299090

[ 中文概述 ]:
2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%