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芳香法宗

芳香法宗用途

Famprofazone是一种非甾体抗炎剂（NSAID）, 属于吡唑啉酮系列, 具有镇痛，抗炎，解热作用。

芳香法宗名称

[ CAS 号 ]:
22881-35-2

[ 中文名 ]:
芳香法宗

[ 英文名 ]:
Famprofazone

[中文别名 ]:

泛普法宗

[英文别名 ]:

Famprofazone
Famprofazona [INN-Spanish]
Famprofazonum [INN-Latin]

芳香法宗物理化学性质

[ 密度 ]:
1.083g/cm3

[ 沸点 ]:
485.1ºC at 760mmHg

[ 分子式 ]:
C₂₄H₃₁N₃O

[ 分子量 ]:
377.52200

[ 闪点 ]:
184.8ºC

[ 精确质量 ]:
377.24700

[ PSA ]:
30.17000

[ LogP ]:
4.36240

[ 蒸汽压 ]:
1.45E-09mmHg at 25°C

[ 折射率 ]:
1.574

芳香法宗MSDS

芳香法宗毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UQ9451000

CHEMICAL NAME :: Pyrazolin-5-one, 4-isopropyl-2-methyl-1-phenyl-3-((1-phenyl-2-propyl)m ethylamino)methyl-

CAS REGISTRY NUMBER :: 22881-35-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C24-H31-N3-O

MOLECULAR WEIGHT :: 377.58

WISWESSER LINE NOTATION :: T5NNVJ A1 BR& DY1&1 E1N1&Y1&1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: SMWOAS Schweizerische Medizinische Wochenschrift. (Schwabe & Co., Steintorst 13, 4010 Basel, Switzerland) V.50- 1920- Volume(issue)/page/year: 84,351,1954

芳香法宗安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
22

[ 安全声明 (欧洲) ]:
36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
UQ9451000

芳香法宗合成路线

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芳香法宗下游产品

芳香法宗文献

Illegal or legitimate use? Precursor compounds to amphetamine and methamphetamine.

Drug Metab. Rev. 32(1) , 15-44, (2000)

The interpretation of methamphetamine and amphetamine positive test results in biological samples is a challenge to clinical and forensic toxicology for several reasons. The effects of pH and dilution...

Detection and identification of famprofazone and its metabolite in human urine.

J. Chromatogr. B, Biomed. Appl. 661(2) , 255-61, (1994)

Detection and identification of famprofazone and its metabolite, p-hydroxydesmethylfamprofazone, were described. The identity of the new metabolite was confirmed by comparing its mass spectrum and gas...

Urinary methamphetamine concentration following famprofazone administration.

J. Anal. Toxicol. 18(5) , 265-8, (1994)

A 37-year-old man had a considerable concentration of methamphetamine in his urine, but he denied taking any abused drug. It was found that he took a pain killer that contains famprofazone, a relative...

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