达库溴铵

达库溴铵用途

Dacuronium bromide is an aminosteroid neuromuscular blocking agent Pancuronium (P178500) with much weaker activity which was never marketed. It acts as a competitive antagonist of the nicotinic acetylcholine receptor (nAChR).

达库溴铵名称

[ CAS 号 ]:
27115-86-2

[ 中文名 ]:
达库溴铵

[ 英文名 ]:
Dacuronium bromide

[英文别名 ]:

dactylomelol
dacuronium bromide

达库溴铵物理化学性质

[ 分子式 ]:
C₃₃H₅₈Br₂N₂O₃

[ 分子量 ]:
690.63300

[ 精确质量 ]:
688.28100

[ PSA ]:
46.53000

达库溴铵毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TN4924000

CHEMICAL NAME :: Piperidinium, 1,1'-(2-beta,16-beta-(3-alpha,17-beta-dihydroxy-5-alp ha-androstanylene)) bis(1-methyl-, dibromide, 3-alpha-acetate

CAS REGISTRY NUMBER :: 27115-86-2

LAST UPDATED :: 199012

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C33-H58-N2-O3.2Br

MOLECULAR WEIGHT :: 690.75

WISWESSER LINE NOTATION :: L E5 B666TJ A1 E1 FQ OOV1 G- AT6KTJ A1& P- AT6KTJ A1 &E 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2910 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 16,1116,1973

达库溴铵安全信息

[ 危险品运输编码 ]:
UN 2811 6.1 / PGIII