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四氢-4-氟甲基-4-羟基-2H-吡喃-2-酮

四氢-4-氟甲基-4-羟基-2H-吡喃-2-酮用途

6-氟甲戊酸酯是一种甲戊酸焦磷酸脱羧酶抑制剂。

四氢-4-氟甲基-4-羟基-2H-吡喃-2-酮名称

[ CAS 号 ]:
2822-77-7

[ 中文名 ]:
6-氟戊酸

[ 英文名 ]:
6-FLUOROMEVALONATE

[英文别名 ]:

6-Fluoromevalonate
ZR 3516
MFCD08276919
Tetrahydro-4-fluoromethyl-4-hydroxy-2H-pyran-2-one
4-(fluoromethyl)-4-hydroxy-2-oxanone

四氢-4-氟甲基-4-羟基-2H-吡喃-2-酮生物活性

[ 描述 ]:

6-氟甲戊酸酯是一种甲戊酸焦磷酸脱羧酶抑制剂。

[ 相关类别 ]:

研究领域 >> 其他

四氢-4-氟甲基-4-羟基-2H-吡喃-2-酮物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
307.8±22.0 °C at 760 mmHg

[ 分子式 ]:
C₆H₉FO₃

[ 分子量 ]:
148.132

[ 闪点 ]:
140.0±22.3 °C

[ 精确质量 ]:
148.053574

[ LogP ]:
-1.06

[ 蒸汽压 ]:
0.0±1.5 mmHg at 25°C

[ 折射率 ]:
1.450

[ 储存条件 ]:
2-8°C

四氢-4-氟甲基-4-羟基-2H-吡喃-2-酮安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H319

[ 警示性声明 ]:
P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ 危险品运输编码 ]:
NONH for all modes of transport

四氢-4-氟甲基-4-羟基-2H-吡喃-2-酮文献

[Pharmacological control of biosynthesis pathway of mevalonate: effect on the proliferation of arterial smooth muscle cells].

C. R. Seances. Soc. Biol. Fil. 191(2) , 169-94, (1997)

The role of mevalonic acid (MVA) and its products (isoprenoids) in cell proliferation prompted us to investigate the effect of drugs affecting diverse enzymatic steps of the MVA pathway on rat aorta s...

Effect of lovastatin and fluoromevalonate on phosphatidylinositol 3-kinase activity stimulated with PDGF.

Clin. Exp. Pharmacol. Physiol. Suppl. 22(1) , S318-20, (1995)

1. Phosphatidylinositol 3-kinase (PI3K) appears to have a crucial role in cellular proliferation induced by platelet-derived growth factor (PDGF). However, the mode of activation of the enzyme has bee...

Inhibition of the isoprenoid biosynthesis pathway; detection of intermediates by UPLC-MS/MS.

Biochim. Biophys. Acta 1811(4) , 227-33, (2011)

The isoprenoid biosynthesis pathway provides the cell with a variety of compounds which are involved in multiple cellular processes. Inhibition of this pathway with statins and bisphosphonates is wide...

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