<生产厂家价格>

B-丁内酯

B-丁内酯名称

[ CAS 号 ]:
3068-88-0

[ 中文名 ]:
β-丁内酯

[ 英文名 ]:
butyrolactone

[中文别名 ]:

[英文别名 ]:

tetrahydrofuran-2-one
g-Butyrolactone
Dihydrofuran-2(3H)-one
β-Methylpropiolactone
MFCD00005170
1-Oxacyclopentan-2-one
gama-Butyrolactone
Nonanoic acid,3-butyl
2-OXOTETRAHYDROFURAN
Dihydro-2(3H)-furanone

B-丁内酯物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
204.0±0.0 °C at 760 mmHg

[ 熔点 ]:
-43.5ºC(lit.)

[ 分子式 ]:
C₄H₆O₂

[ 分子量 ]:
86.089

[ 闪点 ]:
98.3±0.0 °C

[ 精确质量 ]:
86.036781

[ PSA ]:
26.30000

[ LogP ]:
-0.76

[ 外观性状 ]:
无色液体

[ 蒸汽压 ]:
0.3±0.4 mmHg at 25°C

[ 折射率 ]:
1.442

[ 储存条件 ]:
库房通风低温干燥

[ 稳定性 ]:
Stable. Incompatible with strong bases, strong oxidizing agents. Flammable.

[ 水溶解性 ]:
水溶性：可溶；水溶解度：268 g/l 25 °C

B-丁内酯MSDS

详细MSDS(安全技术说明书)

B-丁内酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RQ8050000

CHEMICAL NAME :: 2-Oxetanone, 4-methyl-

CAS REGISTRY NUMBER :: 3068-88-0

LAST UPDATED :: 199709

DATA ITEMS CITED :: 19

MOLECULAR FORMULA :: C4-H6-O2

MOLECULAR WEIGHT :: 86.10

WISWESSER LINE NOTATION :: T4OVTJ D1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 17200 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >20 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 31 gm/kg/61W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 38 gm/kg/76W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 59 gm/kg/49W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 12 gm/kg/30W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 80 gm/kg/67W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 43 gm/kg/36W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: Micronucleus test

MUTATION DATA

TYPE OF TEST :: DNA damage

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 10 mmol/L

REFERENCE :: BBACAQ Biochimica et Biophysica Acta. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1947- Volume(issue)/page/year: 138,611,1967 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 11,225,1976 IARC Cancer Review:Animal No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 11,225,1976 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-FINLAND;Carcinogen JAN 1993 OEL-SWEDEN;Carcinogen JAN 1993

B-丁内酯安全信息

[ 符号 ]:

GHS02, GHS07, GHS08

[ 信号词 ]:
Warning

[ 危害声明 ]:
H226-H315-H319-H351

[ 警示性声明 ]:
P281-P305 + P351 + P338

[ 个人防护装备 ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn: Harmful;

[ 风险声明 (欧洲) ]:
R36/38

[ 安全声明 (欧洲) ]:
26-36

[ 危险品运输编码 ]:
UN 1993 3

[ WGK德国 ]:
3

[ RTECS号 ]:
RQ8050000

[ 包装等级 ]:
III

[ 危险类别 ]:
3.2

B-丁内酯文献

Involvement of catalytic amino acid residues in enzyme-catalyzed polymerization for the synthesis of polyesters.

Biomacromolecules 2(2) , 541-4, (2001)

Recently, a variety of aliphatic polyesters have been synthesized using hydrolases such as lipases and PHB depolymerases, and the reaction mechanism for these enzyme-catalyzed polymerization has been ...

Ring-opening polymerisation of beta-butyrolactone catalysed by distannoxane complexes: study of the mechanism.

Int. J. Biol. Macromol. 25(1-3) , 237-45, (1999)

The mechanism of the ring-opening polymerisation of beta-butyrolactones was studied. The ring-opening polymerisation of BL catatlysed by distannoxane complexes is of a living nature. The polymerisatio...

Novel synthesis of functionalized poly(3-hydroxybutanoic acid) and its copolymers.

Int. J. Biol. Macromol. 25(1-3) , 247-53, (1999)

Novel feasibility of fuctionalized poly(3-hydroxybutanoic acid), PHB, and its copolymers synthesis via ring-opening of beta-butyrolactone (ROP) mediated by activated anionic initiators or enzymes in v...

更多文献