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4-硝基苯基 2-(乙酰氨基)-2-脱氧-beta-D-吡喃葡萄糖苷

用途

4-硝基苯基-N-乙酰基-β-D-葡糖胺是N-乙酰基-贝塔-D-外泌胺酶(NAGase)的人工底物,可用于快速准确地测定N-乙酰基-beta-D-内泌胺酶的速率[1]。

名称

[ CAS 号 ]:
3459-18-5

[ 中文名 ]:
4-硝基苯基-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖苷

[ 英文名 ]:
4-Nitrophenyl 2-acetamido-2-deoxyhexopyranoside

[中文别名 ]:

4-硝基苯基-N-乙酰-β-D-氨基葡糖苷

[英文别名 ]:

4-nitrophenyl-N-acetyl-Beta-D-glucosaminide
EINECS 222-398-7
4-Nitrophenyl 2-acetamido-2-deoxyhexopyranoside
4-N-pyrrolomethylbenzoic acid
4-Nitrophenyl N-Acetyl-β-D-glucosaminide
MFCD00063696
4-Pyrrol-1-ylmethyl-benzoic acid

生物活性

[ 描述 ]:

4-硝基苯基-N-乙酰基-β-D-葡糖胺是N-乙酰基-贝塔-D-外泌胺酶(NAGase)的人工底物,可用于快速准确地测定N-乙酰基-beta-D-内泌胺酶的速率[1]。

[ 相关类别 ]:

研究领域 >> 其他

[参考文献]

[1]. Shibata H, et, al. Rate assay of N-acetyl-beta-D-hexosaminidase with 4-nitrophenyl N-acetyl-beta-D-glucosaminide as an artificial substrate. Clin Chim Acta. 1996 Jul 15;251(1):53-64.

物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
694.7±55.0 °C at 760 mmHg

[ 熔点 ]:
210 - 212ºC

[ 分子式 ]:
C₁₄H₁₈N₂O₈

[ 分子量 ]:
342.301

[ 闪点 ]:
374.0±31.5 °C

[ 精确质量 ]:
342.106323

[ PSA ]:
154.07000

[ LogP ]:
0.00

[ 外观性状 ]:
白色粉末

[ 蒸汽压 ]:
0.0±2.3 mmHg at 25°C

[ 折射率 ]:
1.620

[ 储存条件 ]:
−20°C

[ 水溶解性 ]:
H2O: 5 mg/mL, clear, colorless to very faintly yellow

MSDS

安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

合成路线

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文献

Syntheses of the 3- and 4-thio analogues of 4-nitrophenyl 2-acetamido-2-deoxy-beta-D-gluco- and galactopyranoside.

Carbohydr. Res. 342(15) , 2212-22, (2007)

The syntheses of 4-nitrophenyl beta-glycosides of the 3-thio and 4-thio analogues of the two principal 2-acetamido-2-deoxy-hexoses found in living systems, GlcNAc and GalNAc, are described. While synt...

Chitin oligosaccharide synthesis by rhizobia and zebrafish embryos starts by glycosyl transfer to O4 of the reducing-terminal residue.

Biochemistry 38(13) , 4045-52, (1999)

Lipochitin oligosaccharides are organogenesis-inducing signal molecules produced by rhizobia to establish the formation of nitrogen-fixing root nodules in leguminous plants. Chitin oligosaccharide bio...

Purification and characterization of beta-N-acetylhexosaminidase from Trichoderma harzianum.

Agric. Biol. Chem. 55(11) , 2817-23, (1991)

beta-N-Acetylhexosaminidase was produced by Trichoderma harzianum cultivated with chitin as the growth substrate. The enzyme was purified 13.2-fold to homogeneity by ultrafiltration and sequential chr...

更多文献

4-硝基苯基 2-(乙酰氨基)-2-脱氧-beta-D-吡喃葡萄糖苷

用途

名称

生物活性

物理化学性质

MSDS

详细MSDS(安全技术说明书)

安全信息

合成路线

详细合成路线

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文献

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