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L-酪氨酸乙酯盐酸盐

L-酪氨酸乙酯盐酸盐用途

H-Tyr-OEt。HCl是一种酪氨酸衍生物[1]。

L-酪氨酸乙酯盐酸盐名称

[ CAS 号 ]:
4089-07-0

[ 中文名 ]:
L-酪氨酸乙酯盐酸盐

[ 英文名 ]:
H-Tyr-OEt·HCl

[中文别名 ]:

[英文别名 ]:

L-Tyrosine Ethyl Ester Hydrochloride
Ethyl L-tyrosinate hydrochloride (1:1)
Tyrosine, ethyl ester, hydrochloride, L-
tyrosineethylesterhydrochloride
Tyr-Oet Hcl
EthylL-tyrosinatehydrochloride
EINECS 223-820-2
L-Tyrosine ethyl est
H-Tyr-OEt HCl
L-Tyr-OEt.HCL

L-酪氨酸乙酯盐酸盐生物活性

[ 描述 ]:

H-Tyr-OEt。HCl是一种酪氨酸衍生物[1]。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[体外研究]

氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。

[参考文献]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

L-酪氨酸乙酯盐酸盐物理化学性质

[ 密度 ]:
1.177 g/cm3

[ 沸点 ]:
343.3ºC at 760 mmHg

[ 熔点 ]:
166-170 °C

[ 分子式 ]:
C₁₁H₁₆ClNO₃

[ 分子量 ]:
245.703

[ 闪点 ]:
161.4ºC

[ 精确质量 ]:
245.081863

[ PSA ]:
72.55000

[ LogP ]:
2.32740

[ 外观性状 ]:
白色至灰白色结晶粉末

[ 折射率 ]:
-6.5 ° (C=2, H2O)

[ 储存条件 ]:
−20°C

L-酪氨酸乙酯盐酸盐MSDS

L-酪氨酸乙酯盐酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YP2580000

CHEMICAL NAME :: Tyrosine, ethyl ester, hydrochloride, L-

CAS REGISTRY NUMBER :: 4089-07-0

LAST UPDATED :: 198903

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C11-H15-N-O3.Cl-H

MOLECULAR WEIGHT :: 245.73

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 13800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 18,474,1987

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 7710 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. (Nippon Koteisho Kyokai, 12-15, 2-chome, Shibuya, Shibuya-ku, Tokyo 150, Japan) V.1- 1970- Volume(issue)/page/year: 18,474,1987

L-酪氨酸乙酯盐酸盐安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
YP2580000

[ 包装等级 ]:
III

[ 海关编码 ]:
2922509090

L-酪氨酸乙酯盐酸盐合成路线

L-酪氨酸乙酯盐酸盐上下游产品

L-酪氨酸乙酯盐酸盐上游产品

L-酪氨酸乙酯盐酸盐下游产品

L-酪氨酸乙酯盐酸盐海关

[ 海关编码 ]: 2922509090

[ 中文概述 ]:
2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

L-酪氨酸乙酯盐酸盐文献

Transverse dephasing optimised NMR spectroscopy in solids: natural-abundance 13C correlation spectra.

ChemPhysChem 5(6) , 869-75, (2004)

Dimerisation of N-acetyl-L-tyrosine ethyl ester and Abeta peptides via formation of dityrosine.

Free Radic. Res. 40 , 1-9, (2006)

Alzheimer's disease (AD) is characterised by the formation of amyloid deposits composed primarily of the amyloid beta-peptide (Abeta). This peptide has been shown to bind redox active metals ions such...

Dimorphism of the prodrug L-tyrosine ethyl ester: pressure-temperature state diagram and crystal structure of phase II.

J. Pharm. Sci. 100 , 4774-4782, (2011)

Polymorphism is important in the field of solid-state behavior of drug molecules because of the continuous drive for complete control over drug properties. By comparing different structures of a serie...

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