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4-哌啶基哌啶

4-哌啶基哌啶用途

有机合成、医药合成中间体，可用于合成盐酸伊立替康。

4-哌啶基哌啶名称

[ CAS 号 ]:
4897-50-1

[ 中文名 ]:
4-哌啶基哌啶

[ 英文名 ]:
4-Piperidinopiperidine

[中文别名 ]:

[英文别名 ]:

MFCD00006475
4-Piperidinopiperidine
EINECS 225-522-8
1-piperidin-4-ylpiperidine
1,4'-Bipiperidine
4-Piperidino piperidine

4-哌啶基哌啶物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
251.4±8.0 °C at 760 mmHg

[ 熔点 ]:
64-66 °C(lit.)

[ 分子式 ]:
C₁₀H₂₀N₂

[ 分子量 ]:
168.279

[ 闪点 ]:
99.9±9.4 °C

[ 精确质量 ]:
168.162643

[ PSA ]:
15.27000

[ LogP ]:
1.53

[ 外观性状 ]:
白色或略黄色晶体

[ 蒸汽压 ]:
0.0±0.5 mmHg at 25°C

[ 折射率 ]:
1.500

[ 储存条件 ]:
?20°C

[ 水溶解性 ]:
可溶于：甲醇

4-哌啶基哌啶MSDS

4-哌啶基哌啶安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2933399090

4-哌啶基哌啶合成路线

4-哌啶基哌啶上下游产品

4-哌啶基哌啶上游产品

4-哌啶基哌啶下游产品

4-哌啶基哌啶海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

4-哌啶基哌啶文献

Piperazine N-substituted naphthyridines, pyridothienopyrimidines and pyridothienotriazines: new antiprotozoals active against Philasterides dicentrarchi.

Eur. J. Med. Chem. 38 , 265-275, (2003)

New antiprotozoals active against Philasterides dicentrarchi, the causative agent of scuticociliatosis in farmed turbot and Black Sea bass-bream, have been synthesised and tested. The most active comp...

Synthesis and structure-activity relationships of 5,6,7,8-tetrahydro-4H-thieno[3,2-b]azepine derivatives: novel arginine vasopressin antagonists.

J. Med. Chem. 47 , 101-109, (2004)

A variety of novel heterocyclic compounds having thienoazepine, pyrroloazepine, furoazepine, and thienodiazepine skeletons were synthesized, most of which exhibited potent antagonism of [(3)H]-AVP spe...

Synlett 8 , 1192-1194, (2003)

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