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黏酸

黏酸用途

用于生化研究。用作金属螯合剂，合成杂环化合物的中间体和凝结物硬化延迟剂。

黏酸名称

[ CAS 号 ]:
526-99-8

[ 中文名 ]:
黏酸

[ 英文名 ]:
Mucic acid

[中文别名 ]:

[英文别名 ]:

GALATARIC ACID
(2R,3S,4R,5S)-2,3,4,5-Tetrahydroxyhexanedioic acid
Schleimsaure
Galactarsaeure
Mucic
Galactaric acid
Mucicacid
Mucic acid
meso-galactaric acid
D-Galactaric acid

黏酸物理化学性质

[ 密度 ]:
1.9±0.1 g/cm3

[ 沸点 ]:
766.4±60.0 °C at 760 mmHg

[ 熔点 ]:
220-225 °C (dec.)(lit.)

[ 分子式 ]:
C₆H₁₀O₈

[ 分子量 ]:
210.139

[ 闪点 ]:
431.2±29.4 °C

[ 精确质量 ]:
210.037567

[ PSA ]:
155.52000

[ LogP ]:
-1.46

[ 外观性状 ]:
白色至灰白色结晶粉末

[ 蒸汽压 ]:
0.0±5.9 mmHg at 25°C

[ 折射率 ]:
1.638

[ 储存条件 ]:
Store at RT.

黏酸MSDS

详细MSDS(安全技术说明书)

黏酸毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LW5180000

CHEMICAL NAME :: Galactaric acid

CAS REGISTRY NUMBER :: 526-99-8

BEILSTEIN REFERENCE NO. :: 1728117

LAST UPDATED :: 199701

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C6-H10-O8

MOLECULAR WEIGHT :: 210.16

WISWESSER LINE NOTATION :: QVYQYQYQYQVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 8 gm/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

REFERENCE :: BIJOAK Biochemical Journal. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1906- Volume(issue)/page/year: 34,1196,1940

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 960 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 19,207,1964 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - E0094 No. of Facilities: 12 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 70 (estimated) No. of Female Employees: 70 (estimated)

黏酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi,Xn

[ 风险声明 (欧洲) ]:
22-40

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
2

[ RTECS号 ]:
LW5180000

黏酸上下游产品

黏酸上游产品

黏酸下游产品

黏酸制备

由半乳糖、半乳糖醇或半乳糖醛酸经硝酸氧化生成。

黏酸文献

Coformer screening using thermal analysis based on binary phase diagrams.

Pharm. Res. 31(8) , 1946-57, (2014)

The advent of cocrystals has demonstrated a growing need for efficient and comprehensive coformer screening in search of better development forms, including salt forms. Here, we investigated a coforme...

Synthesis and characterization of copolyanhydrides of carbohydrate-based galactaric acid and adipic acid.

Carbohydr. Res. 402 , 102-10, (2014)

A series of copolyanhydrides, consisting of 2,3,4,5-tetra-O-acetylgalactaric acid (AGA) and adipic acid (AA) as monomer units, was polymerized. Synthesis of AGA monomer consisted of two steps. First, ...

Okibacterium endophyticum sp. nov., a novel endophytic actinobacterium isolated from roots of Salsola affinis C. A. Mey.

Antonie van Leeuwenhoek 107(3) , 835-43, (2015)

A white bacterial strain, designated EGI 650022(T), was isolated from the roots of Salsola affinis C. A. Mey, collected from Urumqi City, Xinjiang, north-western China. The strain was found to be aero...

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黏酸