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促甲状腺素

促甲状腺素用途

促甲状腺激素(TSH)是由垂体前叶的促甲状腺细胞产生的一种促甲状腺激素。促甲状腺素调节甲状腺的内分泌功能[1][2]。

促甲状腺素名称

[ CAS 号 ]:
9002-71-5

[ 中文名 ]:
促甲状腺素

[ 英文名 ]:
tsh

[英文别名 ]:

MFCD00166060
EINECS 232-664-4

促甲状腺素生物活性

[ 描述 ]:

促甲状腺激素(TSH)是由垂体前叶的促甲状腺细胞产生的一种促甲状腺激素。促甲状腺素调节甲状腺的内分泌功能[1][2]。

[ 相关类别 ]:

研究领域 >> 内分泌

信号通路 >> 其他 >> 其他

研究领域 >> 代谢疾病

[参考文献]

[1]. Wolf G. The regulation of the thyroid-stimulating hormone of the anterior pituitary gland by thyroid hormone and by 9-cis-retinoic acid. Nutr Rev. 2002 Nov;60(11):374-7.

[2]. Vassart G, et al. The thyrotropin receptor and the regulation of thyrocyte function and growth. Endocr Rev. 1992 Aug;13(3):596-611.

促甲状腺素物理化学性质

[ 分子式 ]:
C₁₈H₂₆N₆O₆

[ 分子量 ]:
422.436

[ 精确质量 ]:
422.191376

[ 外观性状 ]:
lyophilized powder

[ 储存条件 ]:
2-8°C

促甲状腺素安全信息

[ 危害码 (欧洲) ]:
B

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ RTECS号 ]:
XP3581600

促甲状腺素文献

Excess iodide induces an acute inhibition of the sodium/iodide symporter in thyroid male rat cells by increasing reactive oxygen species.

Endocrinology 156(4) , 1540-51, (2015)

Na+/I- symporter (NIS) mediates iodide (I-) uptake in the thyroid gland, the first and rate-limiting step in the biosynthesis of the thyroid hormones. The expression and function of NIS in thyroid cel...

Effects of magnesium on cytomorphology and enzyme activities in thyroid of rats.

Indian J. Exp. Biol. 52(8) , 787-92, (2014)

Till date knowledge regarding the effects of high dietary magnesium on thyroid gland is incomprehensive though certain epidemiological studies reported development of thyroid gland dysfunctions in peo...

Extreme phenotypic variability of thyroid dysgenesis in six new cases of congenital hypothyroidism due to PAX8 gene loss-of-function mutations.

Eur. J. Endocrinol. 171(4) , 499-507, (2014)

Within the last two decades, heterozygous loss-of-function PAX8 mutations have been reported in patients with a wide degree of thyroid gland dysfunction and growth despite the presence of identical mu...

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