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D-丙氨酰-D-丙氨酸

D-丙氨酰-D-丙氨酸用途

D-Ala-D-Ala构成肽聚糖单体单元的肽部分的末端,并作为底物参与转肽反应。D-Ala-D-Ala由D-丙氨酸-D-丙氨酸连接酶催化。D-Ala-D-Ala是一种细菌内源性代谢产物[1][2]。

D-丙氨酰-D-丙氨酸名称

[ CAS 号 ]:
923-16-0

[ 中文名 ]:
D-丙氨酰-D-丙氨酸

[ 英文名 ]:
H-D-Ala-D-Ala-OH

[中文别名 ]:

D-丙氨酸-D-丙氨酸

[英文别名 ]:

D-ALANYL-D-ALANINE
MFCD00066038
(R)-2-((R)-2-Aminopropanamido)propanoic acid
H-D-ALA-D-ALA-OH
D-ALA-D-ALA
D-Ala-D-Ala-OH

D-丙氨酰-D-丙氨酸生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

[ 靶点 ]

Microbial Metabolite

[参考文献]

[1]. Kitamura Y, et al. Structure of D-alanine-D-alanine ligase from Thermus thermophilus HB8: cumulative conformational change and enzyme-ligand interactions. Acta Crystallogr D Biol Crystallogr. 2009 Oct;65(Pt 10):1098-106.

[2]. Tytgat I, et al. DD-ligases as a potential target for antibiotics: past, present and future. Curr Med Chem. 2009;16(20):2566-80.

D-丙氨酰-D-丙氨酸物理化学性质

[ 密度 ]:
1.208 g/cm3

[ 沸点 ]:
402.6ºC at 760 mmHg

[ 熔点 ]:
286 - 288ºC

[ 分子式 ]:
C₆H₁₂N₂O₃

[ 分子量 ]:
160.17100

[ 闪点 ]:
197.3ºC

[ 精确质量 ]:
160.08500

[ PSA ]:
92.42000

[ LogP ]:
0.01410

[ 外观性状 ]:
白色至灰白色粉末

[ 储存条件 ]:
−20°C

D-丙氨酰-D-丙氨酸MSDS

详细MSDS(安全技术说明书)

D-丙氨酰-D-丙氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2924199090

D-丙氨酰-D-丙氨酸上下游产品

D-丙氨酰-D-丙氨酸上游产品

D-丙氨酰-D-丙氨酸下游产品

D-丙氨酰-D-丙氨酸海关

[ 海关编码 ]: 2924199090

[ 中文概述 ]:
2924199090. 其他无环酰胺（包括无环氨基甲酸酯)(包括其衍生物及盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

D-丙氨酰-D-丙氨酸文献

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.

Nature 457(7231) , 910-4, (2009)

Multiple, complex molecular events characterize cancer development and progression. Deciphering the molecular networks that distinguish organ-confined disease from metastatic disease may lead to the i...

Relationship between glycopeptide production and resistance in the actinomycete Nonomuraea sp. ATCC 39727.

Antimicrob. Agents Chemother. 58(9) , 5191-201, (2014)

Glycopeptides and β-lactams inhibit bacterial peptidoglycan synthesis in Gram-positive bacteria; resistance to these antibiotics is studied intensively in enterococci and staphylococci because of thei...

Bond dissociation of the dipeptide dialanine and its derivative alanine anhydride induced by low energy electrons.

J. Chem. Phys. 134(5) , 054305, (2011)

Dissociative electron attachment to dialanine and alanine anhydride has been studied in the gas phase utilizing a double focusing two sector field mass spectrometer. We show that low-energy electrons ...

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