2539-53-9

• 常用中文名：4-乙氧基-3-羟基苯甲醛
• 常用英文名：4-ethoxy-3-hydroxybenzaldehyde
• CAS号：2539-53-9
• 分子式：C₉H₁₀O₃
• 分子量：166.17400
• 发布时间：2018-05-12 08:00:00
• 更新时间：2024-01-10 07:14:00

名称

• 中文名: 4-乙氧基-3-羟基苯甲醛
• 英文名: 4-ethoxy-3-hydroxybenzaldehyde
• 英文别名: EINECS 219-812-3; Benzaldehyde,4-ethoxy-3-hydroxy; Ethylisovanilline; 4-Aethoxy-3-hydroxy-benzaldehyd; Protocatechualdehyd-4-aethylaether; 3-Oxy-4-aeethoxy-benzaldehyd; Isosafrovanillin; 4-ethoxy-3-hydroxy-benzaldehyde; Isoethylvanillin; 3-hydroxy-4-ethoxy-benzaldehyde

物化性质

• 密度: 1.186 g/cm3
• 沸点: 299.3ºC at 760 mmHg
• 分子式: C₉H₁₀O₃
• 分子量: 166.17400
• 闪点: 121ºC
• 精确质量: 166.06300
• PSA: 46.53000
• LogP: 1.60340
• 蒸汽压: 0.000677mmHg at 25°C
• 折射率: 1.573

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CU6125050 CHEMICAL NAME : Benzaldehyde, 4-ethoxy-3-hydroxy- CAS REGISTRY NUMBER : 2539-53-9 BEILSTEIN REFERENCE NO. : 2048366 LAST UPDATED : 199701 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C9-H10-O3 MOLECULAR WEIGHT : 166.19 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 1330 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value MUTATION DATA TYPE OF TEST : Sister chromatid exchange TEST SYSTEM : Human Lymphocyte DOSE/DURATION : 500 umol/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 206,17,1988

合成路线

120-25-2 ~82% 2539-53-9

文献：Zhejiang Dade Pharmaceutical Group Co. Ltd Patent: US2009/170956 A1, 2009 ; Location in patent: Page/Page column 7-8; fig.1 ;

52987-93-6 ~84% 2539-53-9

文献：Zhejiang Dade Pharmaceutical Group Co., Ltd. Patent: EP2065358 A1, 2009 ; Location in patent: Page/Page column 11; 19 ;

75-03-6 139-85-5 ~19% 2539-53-9

文献：Peng, Ge; Gallop, Mark A.; Chernov-Rogan, Tania; Yanofsky, Stephen D.; Pelletier, Jeffrey Claude; Green, Daniel Michael Patent: US2002/65309 A1, 2002 ; US 20020065309 A1

74-96-4 584-08-7 139-85-5 ~% 2539-53-9

文献：Dynapol Corporation Patent: US4025535 A1, 1977 ;

64-67-5 139-85-5 ~% 2539-53-9

文献：Gurudutt,K.N.; Seshadri,T.R. Phytochemistry (Elsevier), 1974 , vol. 13, p. 2845 - 2847

121-33-5 ~% 2539-53-9

文献：Shanghai Ecust Biomedicine Co., Ltd; Zhejiang Wild Wind Pharmaceutical Co., Ltd Patent: EP2351730 A1, 2011 ;

63477-41-8 ~% 2539-53-9

文献：Hirao Nippon Kagaku Kaishi, 1931 , vol. 52, p. 26,29 Chem.Abstr., 1931 , p. 5156

94-86-0 ~% 2539-53-9

文献：Kafuku; Itikawa Yakugaku Zasshi, 1926 , # 531 p. 35 Chem. Zentralbl., 1926 , vol. 97, # II p. 1138