1164-38-1

• 常用中文名：LACHESINE HYDROCHLORIDE
• 常用英文名：LACHESINE HYDROCHLORIDE
• CAS号：1164-38-1
• 分子式：C₂₀H₂₆ClNO₃
• 分子量：363.87800
• 发布时间：2017-03-05 05:04:43
• 更新时间：2024-01-27 23:10:57

名称

• 英文名: ethyl-[2-(2-hydroxy-2,2-diphenylacetyl)oxyethyl]-dimethylazanium,chloride
• 英文别名: Lachesine; Benzilyloxyethyldimethylethylammonium chloride; EINECS 214-610-1; Ethyl(2-hydroxyethyl)dimethylammonium benzilate chloride; Lachesin; ethyl-(2-benziloyloxy-ethyl)-dimethyl-ammonium,chloride; E-3; 2-Benziloyloxyethylethyldimethylammonium chloride; Laxesin; Aethyl-(2-benziloyloxy-aethyl)-dimethyl-ammonium,Chlorid; Lachesine chloride

物化性质

• 分子式: C₂₀H₂₆ClNO₃
• 分子量: 363.87800
• 精确质量: 363.16000
• PSA: 46.53000
• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:1

  3.氢键受体数量:4

  4.可旋转化学键数量:8

  5.互变异构体数量:无

  6.拓扑分子极性表面积46.5

  7.重原子数量:25

  8.表面电荷:0

  9.复杂度:378

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:2

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : BQ5600000 CHEMICAL NAME : Ammonium, ethyl(2-hydroxyethyl)dimethyl-, chloride, benzilate CAS REGISTRY NUMBER : 1164-38-1 LAST UPDATED : 198706 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C20-H26-N-O3.Cl MOLECULAR WEIGHT : 363.92 WISWESSER LINE NOTATION : QXR&R&VO2K2&1&1 &G HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 85,85,1945 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 40 gm/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 85,85,1945 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 160 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 85,85,1945

合成路线

5928-68-7 ~% 1164-38-1

文献：Ford-Moore; Ing Journal of the Chemical Society, 1947 , p. 59

75-00-3 968-46-7 ~% 1164-38-1

文献：Ford-Moore; Ing Journal of the Chemical Society, 1947 , p. 59

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