122551-95-5

• 常用中文名：4-O-三甲基乙酰基-3-羟基-L-戊胺
• 常用英文名：4-o-pivaloyl-3-hydroxy-l-phenylalanine
• CAS号：122551-95-5
• 分子式：C₁₄H₁₉NO₅
• 分子量：281.30400
• 发布时间：2019-02-16 16:45:56
• 更新时间：2024-01-08 03:50:21

名称

• 中文名: 4-O-三甲基乙酰基-3-羟基-L-戊胺
• 英文名: 4-o-pivaloyl-3-hydroxy-l-phenylalanine
• 英文别名: 3-hydroxy-l-tyrosine4-(2,2-dimethylpropanoate); PDOPA; PivDOPA; 4-O-pivaloyl-L-dopa; L-TYROSINE,3-HYDROXY-,4-(2,2-DIMETHYLPROPANOATE); 4-O-Pivaloyl-L-DOPA L-3-(3-Hydroxy-4-pivaloyloxyphenyl)alanine; nb355; L-3-(3-HYDROXY-4-PIVALOYLOXYPHENYL)ALANINE; 3-[3-Hydroxy-4-(pivaloyloxy)phenyl]-L-alanine

物化性质

• 密度: 1.184 g/cm3
• 沸点: 461.5ºC at 760 mmHg
• 分子式: C₁₄H₁₉NO₅
• 分子量: 281.30400
• 闪点: 232.9ºC
• 精确质量: 281.12600
• PSA: 109.85000
• LogP: 1.99840
• 蒸汽压: 7.28E-09mmHg at 25°C
• 折射率: 1.564

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : YP2833780 CHEMICAL NAME : L-Tyrosine, 3-hydroxy-, 4-(2,2-dimethylpropanoate) CAS REGISTRY NUMBER : 122551-95-5 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C14-H19-N-O5 MOLECULAR WEIGHT : 281.34 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >6 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 78,525,1989

合成路线

59-92-7 3282-30-2 ~58% 122551-95-5

文献：Ihara; Tsuchiya; Sawasaki; Hisaka; Takehana; Tomimoto; Yano Journal of Pharmaceutical Sciences, 1989 , vol. 78, # 7 p. 525 - 529

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