83881-37-2

• 常用中文名：西替利嗪酰胺
• 常用英文名：Cetirizine Amide
• CAS号：83881-37-2
• 分子式：C₂₂H₂₆ClN₃O₄
• 分子量：431.91300
• 发布时间：2017-07-12 08:29:02
• 更新时间：2026-07-05 20:07:32

名称

• 中文名: 西替利嗪酰胺
• 英文名: Cetirizine Amide
• 中文别名: 西替利嗪杂质C; 西替利嗪酰胺(西替利嗪杂质C); 西替利嗪相关化合物C 标准品; 西替利嗪胺杂质; 西替利嗪聚酰胺杂质; 左西替利杂质9; 西替利嗪杂质29; 2-(2-(4-(((4-氯苯基)(苯基)甲基)哌嗪-1-基)乙氧基)乙酰胺(西替利嗪杂质)
• 英文别名: Cetirizine RC C(base); Cetirizine Related Compound C (2-(2-{4-[(4-Chlorophenyl)phenylmethyl]piperazin-1-yl}ethoxy)acetamid; 2-[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-acetamide; (-)-2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetamide; Cetirizine Impurity C; Cetirizine Impurity; 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)acetamide (Cetirizine Impurity）; 2-(2-(4-((4-Chlorophenyl)(phenyl)methyl)-piperazin-1-yl)ethoxy)acetamide; 2-[4-[(4-Chlorophenyl-phenyl methyl)-1-piperazinyl]ethoxy]acetamide; Levocetirizine Impurity 9; CETIRIZINE AMIDE IMP; UCB-L 172; Cetirizine Related Compound C HCl; CETIRIZINE AMIDE IMPURITY; 2-[2-(4-[^a-(4-Chlorophenyl)benzyl]-1-piperazinyl)ethoxy]acetaMide; Cetirizine Impurity 29; UCB-L; 2-(2-{4-[(4-chlorophenyl)phenylmethyl]piperazin-1-yl}ethoxy)acetamide

物化性质

• 分子式: C₂₂H₂₆ClN₃O₄
• 分子量: 431.91300
• 精确质量: 431.16100
• PSA: 96.10000
• LogP: 2.57820

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : AB5836214 CHEMICAL NAME : Acetamide, 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl) ethoxy)- CAS REGISTRY NUMBER : 83881-37-2 LAST UPDATED : 199606 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C21-H26-Cl-N3-O2 MOLECULAR WEIGHT : 387.95 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 232 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4525358

安全

• 危险品运输编码: NONH for all modes of transport
• 海关编码: 2933599090

合成路线

36961-64-5 303-26-4 ~96% 83881-37-2

文献：US2011/172425 A1, ; Page/Page column 8 ;

83881-52-1 ~79% 83881-37-2

文献：Organic Process Research and Development, , vol. 5, # 2 p. 110 - 115

上下游产品

上游产品  3
36961-64-5 303-26-4 83881-52-1
下游产品  2
83881-51-0 83881-52-1

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%