918431-92-2

• 常用中文名：tert-butyl 4-carbamoyl-4-fluoropiperidine-1-carboxylate
• 常用英文名：tert-butyl 4-carbamoyl-4-fluoropiperidine-1-carboxylate
• CAS号：918431-92-2
• 分子式：C₁₁H₁₉FN₂O₃
• 分子量：246.27900
• 发布时间：2016-12-28 10:32:23
• 更新时间：2026-08-14 05:19:38

名称

• 英文名: tert-butyl 4-carbamoyl-4-fluoropiperidine-1-carboxylate
• 英文别名: 1-Piperidinecboxylic acid, 4-(aminocbonyl)-4-fluoro-, 1,1-dimethylethyl ester; tert-Butyl 4-cbamoyl-4-fluoropiperidine-1-cboxylate

物化性质

• 分子式: C₁₁H₁₉FN₂O₃
• 分子量: 246.27900
• 精确质量: 246.13800
• PSA: 73.62000
• LogP: 2.29850

合成路线

416852-82-9 ~% 918431-92-2

文献：Shipe, William D.; Barrow, James C.; Yang, Zhi-Qiang; Lindsley, Craig W.; Yang, F. Vivien; Schlegel, Kelly-Ann S.; Shu, Youheng; Rittle, Kenneth E.; Bock, Mark G.; Hartman, George D.; Tang, Cuyue; Ballard, Jeanine E.; Kuo, Yuhsin; Adarayan, Emily D.; Prueksaritanont, Thomayant; Zrada, Matthew M.; Uebele, Victor N.; Nuss, Cindy E.; Connolly, Thomas M.; Doran, Scott M.; Fox, Steven V.; Kraus, Richard L.; Marino, Michael J.; Graufelds, Valerie Kuzmick; Vargas, Hugo M.; Bunting, Patricia B.; Hasbun-Manning, Martha; Evans, Rose M.; Koblan, Kenneth S.; Renger, John J. Journal of Medicinal Chemistry, 2008 , vol. 51, # 13 p. 3692 - 3695