4897-31-8

• 常用中文名：4-氯-1-甲基-5-硝基-1H-咪唑
• 常用英文名：Chlomizole
• CAS号：4897-31-8
• 分子式：C₄H₄ClN₃O₂
• 分子量：161.54600
• 发布时间：2017-05-16 16:12:07
• 更新时间：2024-01-05 20:53:18

名称

• 中文名: 4-氯-1-甲基-5-硝基-1H-咪唑
• 英文名: 4-chloro-1-methyl-5-nitroimidazole
• 英文别名: 4-Chlor-1-methyl-5-nitro-1H-imidazol; 1-Methyl-4-chlor-5-nitro-imidazol; 4-chloro-1-methyl-5-nitro-1H-imidazole; Khlomizol; Chloronizole; 1H-Imidazole,4-chloro-1-methyl-5-nitro; Imidazole,4-chloro-1-methyl-5-nitro; Chlomizole; 1-methyl-4-chloro-5-nitroimidazole

物化性质

• 密度: 1.65g/cm3
• 沸点: 362.3ºC at 760 mmHg
• 分子式: C₄H₄ClN₃O₂
• 分子量: 161.54600
• 闪点: 172.9ºC
• 精确质量: 160.99900
• PSA: 63.64000
• LogP: 1.50490
• 折射率: 1.648
• 储存条件: 2-8°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NI4397000 CHEMICAL NAME : Imidazole, 4-chloro-1-methyl-5-nitro- CAS REGISTRY NUMBER : 4897-31-8 BEILSTEIN REFERENCE NO. : 0144324 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C4-H4-Cl-N3-O2 MOLECULAR WEIGHT : 161.56 WISWESSER LINE NOTATION : T5N CNJ A1 DG ENW HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 275 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 31,158,1968

合成路线

57531-38-1 77-78-1 ~80% 4897-31-8

文献：Samant, Bhupesh S.; Sukhthankar, Mugdha G. Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 3 p. 1015 - 1018

186581-53-3 57531-38-1 ~40% 4897-25-0 4897-31-8

文献：Suwinski, Jerzy; Salwinska, Ewa; Watras, Jan; Widel, Maria Polish Journal of Chemistry, 1982 , vol. 56, # 10-12 p. 1261 - 1272

57531-38-1 77-78-1 ~11% 4897-25-0 4897-31-8

文献：Suwinski, Jerzy; Salwinska, Ewa; Watras, Jan; Widel, Maria Polish Journal of Chemistry, 1982 , vol. 56, # 10-12 p. 1261 - 1272

7664-93-9 5862-35-1 ~% 4897-31-8

文献：Sarasin; Wegmann Helvetica Chimica Acta, 1924 , vol. 7, p. 714

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