93129-68-1

• 常用中文名：N-(4-氰基-2-氟苯基)乙酰胺
• 常用英文名：N-(4-cyano-2-fluorophenyl)acetamide
• CAS号：93129-68-1
• 分子式：C₉H₇FN₂O
• 分子量：178.163
• 发布时间：2018-12-18 14:22:08
• 更新时间：2024-02-02 17:36:19

名称

• 中文名: N-(4-氰基-2-氟苯基)乙酰胺
• 英文名: N-(4-cyano-2-fluorophenyl)acetamide
• 英文别名: Acetamide, N-(4-cyano-2-fluorophenyl)-; 4-acetylamino-3-fluoro-benzonitrile; 2-fluoro-4-cyanoacetanilide; N-(4-Cyano-2-fluorophenyl)acetamide

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 366.9±32.0 °C at 760 mmHg
• 分子式: C₉H₇FN₂O
• 分子量: 178.163
• 闪点: 175.7±25.1 °C
• 精确质量: 178.054245
• PSA: 56.38000
• LogP: 0.95
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.536

合成路线

326-66-9 143-33-9 ~90% 93129-68-1

文献：Zanon, Jacopo; Klapars, Artis; Buchwald, Stephen L. Journal of the American Chemical Society, 2003 , vol. 125, # 10 p. 2890 - 2891

326-66-9 557-21-1 ~86% 93129-68-1

文献：BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. Patent: WO2005/30213 A1, 2005 ; Location in patent: Page/Page column 186 ; WO 2005/030213 A1

544-92-3 97760-94-6 ~72% 93129-68-1

文献：WARNER-LAMBERT COMPANY LLC Patent: WO2004/41793 A1, 2004 ; Location in patent: Page 142 ; WO 2004/041793 A1

557-21-1 97760-94-6 ~% 93129-68-1

文献：Suh, Young-Ger; Lee, Yong-Sil; Min, Kyung-Hoon; Park, Ok-Hui; Kim, Jin-Kwan; Seung, Ho-Sun; Seo, Seung-Yong; Lee, Bo-Young; Nam, Yeon-Hee; Lee, Kwang-Ok; Kim, Hee-Doo; Park, Hyeung-Geun; Lee, Jeewoo; Oh, Uhtaek; Lim, Ju-Ok; Kang, Sang-Uk; Kil, Min-Jung; Koo, Jae-Yeon; Shin, Song Seok; Joo, Yung-Hyup; Kim, Jin Kwan; Jeong, Yeon-Su; Kim, Sun-Young; Park, Young-Ho Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5823 - 5836

29632-74-4 ~% 93129-68-1

文献：Suh, Young-Ger; Lee, Yong-Sil; Min, Kyung-Hoon; Park, Ok-Hui; Kim, Jin-Kwan; Seung, Ho-Sun; Seo, Seung-Yong; Lee, Bo-Young; Nam, Yeon-Hee; Lee, Kwang-Ok; Kim, Hee-Doo; Park, Hyeung-Geun; Lee, Jeewoo; Oh, Uhtaek; Lim, Ju-Ok; Kang, Sang-Uk; Kil, Min-Jung; Koo, Jae-Yeon; Shin, Song Seok; Joo, Yung-Hyup; Kim, Jin Kwan; Jeong, Yeon-Su; Kim, Sun-Young; Park, Young-Ho Journal of Medicinal Chemistry, 2005 , vol. 48, # 18 p. 5823 - 5836

348-54-9 ~% 93129-68-1

文献：Kruger; Keck; Noll; Pieper Arzneimittel-Forschung/Drug Research, 1984 , vol. 34, # 11 A p. 1612 - 1624