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23590-99-0

23590-99-0结构式

常用中文名：肌苷二醛
常用英文名：inosine, periodate oxidized
CAS号：23590-99-0
分子式：C₁₀H₁₀N₄O₅
分子量：266.21000
相关类别：原料药抗肿瘤药抗代谢类抗肿瘤药
发布时间：2018-07-03 13:36:20
更新时间：2024-04-02 08:21:46

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中文名	肌苷二醛
英文名	Diglycolaldehyde, .α.-(hydroxymethyl)-.α.'-(6-hydroxy-9H-purin-9-yl)
中文别名	次黄嘌呤核苷醛
英文别名	INOSINE,PERIODATE OXIDIZED inosinedialdehyde diglycoaldehyde inosine glycodialdehyde inox Inosin-dialdehyd Inosin-2,3-dialdehyd ehyde

密度	1.69 g/cm3
沸点	574.4ºC at 760 mmHg
分子式	C₁₀H₁₀N₄O₅
分子量	266.21000
闪点	301.2ºC
精确质量	266.06500
PSA	127.17000
蒸汽压	4.9E-14mmHg at 25°C
折射率	1.71

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UO7451000

CHEMICAL NAME :: 9H-Purine-9-acetaldehyde, alpha-(1-formyl-2-hydroxyethoxy)-1,6-dihydro-6-oxo-, (R,R)-

CAS REGISTRY NUMBER :: 23590-99-0

LAST UPDATED :: 199801

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C10-H10-N4-O5

MOLECULAR WEIGHT :: 266.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 567 mg/kg

TOXIC EFFECTS :: Gastrointestinal - other changes Blood - normocytic anemia Blood - thrombocytopenia

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 625 mg/kg/5D-I

TOXIC EFFECTS :: Blood - leukopenia Blood - changes in bone marrow (not otherwise specified) Kidney, Ureter, Bladder - other changes

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - mouse Lymphocyte

DOSE/DURATION :: 1 mmol/L

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 34,1717,1985

海关编码	2933990090

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%