484-23-1

• 常用中文名：双肼屈嗪
• 常用英文名：dihydralazine
• CAS号：484-23-1
• 分子式：C₈H₁₀N₆
• 分子量：190.205
• 相关类别： 原料药 循环系统用药 抗高血压病药
• 发布时间：2018-03-29 08:00:00
• 更新时间：2025-08-27 09:40:52

名称

• 中文名: 双肼酞嗪
• 英文名: (4-hydrazinylphthalazin-1-yl)hydrazine
• 中文别名: 双肼屈嗪; 血压达静
• 英文别名: 1,4-Phthalazinedione, 2,3-dihydro-, dihydrazone; Dihydralazin; Nepresol; 1,4-dihydrazinophthanazine; 1,4-Phthalazinedione, 2,3-dihydro-, dihydrazone, (1Z,4Z)-; 1,4-Dihydrazinophthalazine; Nepresolin; Dihydrallazine; Dihydrallazin; 4-Hydrazino-1-hydrazono-1,2-dihydrophthalazine; phthalazine, 1,4-bis(hydrazino)-; Phthalazine, 1,4-bis(hydrazinyl)-; 1,4-dihydrazinophtalazine; (1Z,4E)-1,4-Dihydrazono-1,2,3,4-tetrahydrophthalazine; Nepressol; Hypopresol; 1,4-bis(hydrazino)phthalazine; 1,4-Phthalazinedione, 2,3-dihydro-, dihydrazone, (1Z,4E)-; (1Z,4Z)-1,4-Dihydrazono-1,2,3,4-tetrahydrophthalazine; Ophthazin; dihydralazine; 1,4-dihydrazinylphthalazine

物化性质

• 密度: 1.6±0.1 g/cm3
• 沸点: 419.9±28.0 °C at 760 mmHg
• 熔点: 180ºC
• 分子式: C₈H₁₀N₆
• 分子量: 190.205
• 闪点: 207.7±24.0 °C
• 精确质量: 190.096695
• PSA: 108.34000
• LogP: 0.73
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.810

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TH8849900 CHEMICAL NAME : Phthalazine, 1,4-dihydrazino- CAS REGISTRY NUMBER : 484-23-1 BEILSTEIN REFERENCE NO. : 0183442 LAST UPDATED : 199703 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C8-H10-N6 MOLECULAR WEIGHT : 190.24 WISWESSER LINE NOTATION : T66 CNNJ BMZ EMZ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 106 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 300 mg/kg TOXIC EFFECTS : Vascular - BP lowering not characterized in autonomic section TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous DOSE : 250 ug/kg SEX/DURATION : female 32 week(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - cardiovascular (circulatory) system MUTATION DATA TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 125 ug/tube REFERENCE : ABPLAF Acta Biochimica Polonica. (Polish Biochemical Society, Posteura 3, 01-093 Warsaw, Poland) V.1- 1954- Volume(issue)/page/year: 42,291,1995

安全

• 海关编码: 2933990090

合成路线

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海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%