633283-63-3

• 常用中文名：叔-丁基 4-(2-氯吡啶-4-基)哌嗪-1-甲酸基酯
• 常用英文名：1-Piperazinecarboxylic acid, 4-(2-chloro-4-pyridinyl)-, 1,1-dimethylethyl ester
• CAS号：633283-63-3
• 分子式：C₁₄H₂₀ClN₃O₂
• 分子量：297.78100
• 发布时间：2018-12-18 09:34:49
• 更新时间：2023-01-16 01:16:36

名称

• 中文名: 4-(2-氯-4-吡啶)- 1- 哌嗪羧酸 1,1-二甲基乙酯
• 英文名: tert-butyl 4-(2-chloropyridin-4-yl)piperazine-1-carboxylate
• 英文别名: 1-N-BOC-4-(2-CHLORO-4-PYRIDINYL)PIPERAZINE; 4-(2-chloro-pyridin-4-yl)piperazine-1-carboxylic acid tert-butyl ester; 1-N-(tert-butoxycarbonyl)-4-N-(2-chloropyridin-4-yl)piperazine; 4-(2-CHLORO-4-PYRIDINYL)-1-PIPERAZINECARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER; N-BOC-4-(2-CHLORO-4-PYRIDINYL) PIPERAZINE; 1-Piperazinecarboxylic acid, 4-(2-chloro-4-pyridinyl)-, 1,1-dimethylethyl ester

物化性质

• 分子式: C₁₄H₂₀ClN₃O₂
• 分子量: 297.78100
• 精确质量: 297.12400
• PSA: 45.67000
• LogP: 2.79500
• 储存条件: 室温，密封，干燥

合成路线

73583-37-6 57260-71-6 ~98% 633283-63-3

文献：JANSSEN PHARMACEUTICA NV Patent: WO2009/152325 A1, 2009 ; Location in patent: Page/Page column 47-48 ; WO 2009/152325 A1

26452-80-2 57260-71-6 ~51% 936368-68-2 633283-63-3

文献：Gobbi, Luca; Jaeschke, Georg; Rodriguez Sarmiento, Rosa Maria; Steward, Lucinda Patent: US2010/75979 A1, 2010 ; Location in patent: Page/Page column 9; 11 ; US 20100075979 A1

153034-86-7 57260-71-6 ~% 633283-63-3

文献：ALMAC DISCOVERY LIMITED; HARRISON, Timothy; BURKAMP, Frank; JORDAN, Linda; BELL, Mark; JANSSEN, Dominic; MIEL, Hugues; MCFARLAND, Mary Patent: WO2012/69852 A1, 2012 ; Location in patent: Page/Page column 36 ;