682357-49-9

• 常用中文名：2-叔丁基-1H-吲哚-5-胺
• 常用英文名：2-tert-Butyl-1H-indol-5-amine
• CAS号：682357-49-9
• 分子式：C₁₂H₁₆N₂
• 分子量：188.269
• 发布时间：2018-02-20 08:00:00
• 更新时间：2024-01-10 11:13:11

名称

• 中文名: 2-叔丁基-1H-吲哚-5-胺
• 英文名: 2-(2-Methyl-2-propanyl)-1H-indol-5-amine
• 英文别名: 2-(tert-Butyl)-1H-indol-5-amine; 2-tert-Butyl-1-chlor-3-phenyl-1H-phosphiren; 2-tert-butyl-1-chloro-3-phenyl-1H-phosphirene; 1-chloro-3-(1,1-dimethylethyl)-2-phenyl-1H-phosphirene; 2-(2-Methyl-2-propanyl)-1H-indol-5-amine; 2-tert-Butyl-1H-indol-5-amine; 1H-Phosphirene,1-chloro-2-(1,1-dimethylethyl)-3-phenyl; 2-tert-butyl-1H-indol-5-ylamine; (phenyl)(t-Bu)-1-chlor-1H-phosphirene; 1H-Indol-5-amine, 2-(1,1-dimethylethyl)-; 5-amino-2-t-butylindole; (Phenyl)(t-Bu)-1-chlor-1H-phosphiren

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 365.7±22.0 °C at 760 mmHg
• 分子式: C₁₂H₁₆N₂
• 分子量: 188.269
• 闪点: 202.5±9.5 °C
• 精确质量: 188.131348
• PSA: 41.81000
• LogP: 2.39
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.635

合成路线

174274-85-2 ~94% 682357-49-9

文献：Rigel pharmaceuticals, Inc. Patent: WO2004/35571 A1, 2004 ; Location in patent: Page 25 ;

1805-65-8 ~% 682357-49-9

文献：Kuyper, Lee F.; Baccanari, David P.; Jones, Michael L.; Hunter, Robert N.; Tansik, Robert L.; Joyner, Suzanne S.; Boytos, Christine M.; Rudolph, Sharon K.; Knick, Vince; Wilson, H. Robert; Caddell, J. Marc; Friedman, Henry S.; Comley, John C. W.; Stables, Jeremy N. Journal of Medicinal Chemistry, 1996 , vol. 39, # 4 p. 892 - 903

917-92-0 ~% 682357-49-9

文献：Kuyper, Lee F.; Baccanari, David P.; Jones, Michael L.; Hunter, Robert N.; Tansik, Robert L.; Joyner, Suzanne S.; Boytos, Christine M.; Rudolph, Sharon K.; Knick, Vince; Wilson, H. Robert; Caddell, J. Marc; Friedman, Henry S.; Comley, John C. W.; Stables, Jeremy N. Journal of Medicinal Chemistry, 1996 , vol. 39, # 4 p. 892 - 903

615-43-0 ~% 682357-49-9

文献：Kuyper, Lee F.; Baccanari, David P.; Jones, Michael L.; Hunter, Robert N.; Tansik, Robert L.; Joyner, Suzanne S.; Boytos, Christine M.; Rudolph, Sharon K.; Knick, Vince; Wilson, H. Robert; Caddell, J. Marc; Friedman, Henry S.; Comley, John C. W.; Stables, Jeremy N. Journal of Medicinal Chemistry, 1996 , vol. 39, # 4 p. 892 - 903

116491-51-1 ~% 682357-49-9

文献：Kuyper, Lee F.; Baccanari, David P.; Jones, Michael L.; Hunter, Robert N.; Tansik, Robert L.; Joyner, Suzanne S.; Boytos, Christine M.; Rudolph, Sharon K.; Knick, Vince; Wilson, H. Robert; Caddell, J. Marc; Friedman, Henry S.; Comley, John C. W.; Stables, Jeremy N. Journal of Medicinal Chemistry, 1996 , vol. 39, # 4 p. 892 - 903

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