124489-20-9

• 常用中文名：N2-OH-PhIP
• 常用英文名：N2-OH-PhIP
• CAS号：124489-20-9
• 分子式：C₁₃H₁₂N₄O
• 分子量：240.26100
• 发布时间：2017-07-29 11:45:40
• 更新时间：2024-01-08 17:13:41
• N2-OH-PhIP is a PhIP metabolite.

名称

• 英文名: N-(1-methyl-6-phenylimidazo[4,5-b]pyridin-2-yl)hydroxylamine
• 英文别名: 2H-Imidazo[4,5-b]pyridin-2-one,1,3-dihydro-1-methyl-6-phenyl-,oxime; 2-hydroxyamino-PhIP; 2-Hydroxamino-1-methyl-6-phenylimidazo(4,5-b)pyridine; 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine; 1,3-Dihydro-1-methyl-6-phenyl-2H-imidazo(4,5-b)pyridin-2-one oxime; N-Hydroxy phip

物化性质

• 密度: 1.35g/cm3
• 沸点: 497.8ºC at 760mmHg
• 分子式: C₁₃H₁₂N₄O
• 分子量: 240.26100
• 闪点: 254.8ºC
• 精确质量: 240.10100
• PSA: 62.97000
• LogP: 2.50940
• 蒸汽压: 9.98E-11mmHg at 25°C
• 折射率: 1.698

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NJ5831020 CHEMICAL NAME : 2H-Imidazo(4,5-b)pyridin-2-one, 1,3-dihydro-1-methyl-6-phenyl-, oxime CAS REGISTRY NUMBER : 124489-20-9 LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C13-H12-N4-O MOLECULAR WEIGHT : 240.29 HEALTH HAZARD DATA ACUTE TOXICITY DATA MUTATION DATA TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - hamster Lung DOSE/DURATION : 1250 ug/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 367,115,1996

合成路线

129018-59-3 ~92% 124489-20-9

文献：Nguyen, Thach-Mien; Novak, Michael Journal of Organic Chemistry, 2007 , vol. 72, # 13 p. 4698 - 4706

105650-23-5 ~% 124489-20-9

文献：Peng, Lijuan; Dasari, Surendra; Tabb, David L.; Turesky, Robert J. Chemical Research in Toxicology, 2012 , vol. 25, # 10 p. 2179 - 2193

125572-33-0 ~% 124489-20-9

文献：Nguyen, Thach-Mien; Novak, Michael Journal of Organic Chemistry, 2007 , vol. 72, # 13 p. 4698 - 4706

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