194159-18-7

• 常用中文名：单更昔洛韦丙酸酯
• 常用英文名：Ganciclovir Mono-O-propionate
• CAS号：194159-18-7
• 分子式：C₁₂H₁₇N₅O₅
• 分子量：311.294
• 发布时间：2018-07-15 17:56:53
• 更新时间：2026-07-10 19:16:48

名称

• 中文名: 单丙酸酯更昔洛韦
• 英文名: [2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]-3-hydroxypropyl] propanoate
• 中文别名: 盐酸缬更昔洛韦杂质J; 更昔洛韦杂质9; 更昔洛韦杂质; 更昔洛韦单-O-丙酸酯; 缬更昔洛韦RC J; 更昔洛韦 杂质 B(更昔洛韦单丙酸酯); 更昔洛韦杂质B(单丙酸更昔洛韦); 更昔洛韦杂质02; 更昔洛韦杂质B; 更昔洛韦杂质B(更昔诺韦杂质); 更昔洛韦杂质2(更昔洛韦杂质B)
• 英文别名: valganciclovirhydrochloride iMpurit J; (2RS)-2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]-3-hydroxy-propyl Propionate (Ganciclovir; Valganciclovir Hydrochloric iMpurit J; Ganciclovir Monopropionate; Ganciclovir Impurity B (Ganciclovir Monopropionate); Ganciclovir impurities817; 2-(2-Amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-3-propionyloxy-1-propanol; UNII-88D0H2WAXF; ganciclovir monopropionate; UNII:88D0H2WAXF; Ganciclovir Impurity 9; Ganciclovir impurity B; Ganciclovir Monoproprionate; (2RS)-2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]-3-hydroxy-propyl Propionate (Ganciclovir Monopropionate); Ganciclovir Impurity 2; 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[[1-(hydroxymethyl)-2-(1-oxopropoxy)ethoxy]methyl]; Ganciclovir Imp. B : (2RS)-2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy-3-hydroxypropyl propionate; Valganciclovir RC J; 2-[(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]-3-hydroxypropyl propionate; 2-((2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-3-hydroxypropyl propionate,(2RS); Gancyclovir Impurity 6; 2-((2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy)-3- hydroxypropyl propionate; Ganciclovir Impurity 2(Ganciclovir Impurity B); Ganciclovir Impurity B (Ganciclovir Impurity）

物化性质

• 密度: 1.6±0.1 g/cm3
• 沸点: 607.1±65.0 °C at 760 mmHg
• 分子式: C₁₂H₁₇N₅O₅
• 分子量: 311.294
• 闪点: 321.0±34.3 °C
• 精确质量: 311.122955
• PSA: 146.34000
• LogP: -0.96
• 蒸汽压: 0.0±1.8 mmHg at 25°C
• 折射率: 1.673

合成路线

82410-32-0 ~% 194159-18-7

文献：Syntex (U.S.A.) Inc. Patent: US5840890 A1, 1998 ;