71576-05-1

• 常用中文名：3-[[4-(4-chlorophenyl)-1,3-thiazol-2-yl]carbamoyl]propanoic acid
• 常用英文名：3-[[4-(4-chlorophenyl)-1,3-thiazol-2-yl]carbamoyl]propanoic acid
• CAS号：71576-05-1
• 分子式：C₁₃H₁₁ClN₂O₃S
• 分子量：310.75600
• 发布时间：2016-04-19 04:41:21
• 更新时间：2024-01-10 21:08:53

名称

• 英文名: 4-[[4-(4-chlorophenyl)-1,3-thiazol-2-yl]amino]-4-oxobutanoic acid
• 英文别名: 3-[[4-(4-CHLOROPHENYL)-1,3-THIAZOL-2-YL]CARBAMOYL]PROPANOIC ACID; 4-((4-(4-Chlorophenyl)-2-thiazolyl)amino)-4-oxobutanoic acid; 4-{[4-(4-chlorophenyl)-1,3-thiazol-2-yl]amino}-4-oxobutanoic acid; Butanoic acid,4-((4-(4-chlorophenyl)-2-thiazolyl)amino)-4-oxo; Acide N(p-chlorophenyl-4 thiazolyl-2) succinamique [French]; F 1683; 4-(4-(4-chlorophenyl)thiazol-2-ylamino)-4-oxobutanoic acid

物化性质

• 密度: 1.479g/cm3
• 分子式: C₁₃H₁₁ClN₂O₃S
• 分子量: 310.75600
• 精确质量: 310.01800
• PSA: 111.02000
• LogP: 3.91630
• 折射率: 1.657

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : EK7761172 CHEMICAL NAME : Butanoic acid, 4-((4-(4-chlorophenyl)-2-thiazolyl)amino)-4-oxo- CAS REGISTRY NUMBER : 71576-05-1 LAST UPDATED : 199609 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C13-H11-Cl-N2-O3-S MOLECULAR WEIGHT : 310.77 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #0001727

合成路线

905405-03-0 ~75% 71576-05-1

文献：Xu, Qinyuan; Huang, Li; Liu, Juan; Ma, Liang; Chen, Tao; Chen, Jinying; Peng, Fei; Cao, Dong; Yang, Zhuang; Qiu, Neng; Qiu, Jingxiang; Wang, Guangcheng; Liang, Xiaolin; Peng, Aihua; Xiang, Mingli; Wei, Yuquan; Chen, Lijuan European Journal of Medicinal Chemistry, 2012 , vol. 52, p. 70 - 81

108-30-5 2103-99-3 ~30% 71576-05-1

文献：Wang, Yue; Wang, Fang; Guan, Xin-Lei; Wang, Can-Ming; Cao, Hui; Li, Ming-Xing; Chen, Jian-Guo; Jiang, Feng-Chao; Li, Lei; Yu, Jun-Ping Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 21 p. 6513 - 6522,10 Title/Abstract Show Details Wang, Yue; Wang, Fang; Yu, Jun-Ping; Jiang, Feng-Chao; Guan, Xin-Lei; Wang, Can-Ming; Li, Lei; Cao, Hui; Li, Ming-Xing; Chen, Jian-Guo Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 21 p. 6513 - 6522

99-91-2 ~% 71576-05-1

文献：Xu, Qinyuan; Huang, Li; Liu, Juan; Ma, Liang; Chen, Tao; Chen, Jinying; Peng, Fei; Cao, Dong; Yang, Zhuang; Qiu, Neng; Qiu, Jingxiang; Wang, Guangcheng; Liang, Xiaolin; Peng, Aihua; Xiang, Mingli; Wei, Yuquan; Chen, Lijuan European Journal of Medicinal Chemistry, 2012 , vol. 52, p. 70 - 81

536-38-9 ~% 71576-05-1

文献：Xu, Qinyuan; Huang, Li; Liu, Juan; Ma, Liang; Chen, Tao; Chen, Jinying; Peng, Fei; Cao, Dong; Yang, Zhuang; Qiu, Neng; Qiu, Jingxiang; Wang, Guangcheng; Liang, Xiaolin; Peng, Aihua; Xiang, Mingli; Wei, Yuquan; Chen, Lijuan European Journal of Medicinal Chemistry, 2012 , vol. 52, p. 70 - 81

2103-99-3 ~% 71576-05-1

文献：Xu, Qinyuan; Huang, Li; Liu, Juan; Ma, Liang; Chen, Tao; Chen, Jinying; Peng, Fei; Cao, Dong; Yang, Zhuang; Qiu, Neng; Qiu, Jingxiang; Wang, Guangcheng; Liang, Xiaolin; Peng, Aihua; Xiang, Mingli; Wei, Yuquan; Chen, Lijuan European Journal of Medicinal Chemistry, 2012 , vol. 52, p. 70 - 81

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108-30-5 2103-99-3 99-91-2 536-38-9
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