59512-16-2

• 常用中文名：外消旋酮洛芬酰胺13C,d3
• 常用英文名：2-(3-benzoylphenyl)propanamide
• CAS号：59512-16-2
• 分子式：C₁₆H₁₅NO₂
• 分子量：253.29600
• 发布时间：2016-02-12 11:11:41
• 更新时间：2026-08-06 20:21:28

名称

• 中文名: 外消旋酮洛芬酰胺13C,d3
• 英文名: 2-(3-benzoylphenyl)propanamide
• 中文别名: (RS)-2-(3-苯甲酰苯基)丙酰胺; (RS)-2-(3-苯甲酰基苯基)丙酰胺; 酮洛芬杂质E; 酮基布洛芬杂质E 标准品; 酮洛芬杂质5; 2-(3-苯甲酰基苯基)丙酰胺 (酮洛芬杂质); 酮基布洛芬杂质E; 2-(3-苯甲酰基苯基)丙酰胺; 酮洛芬 E; 酮基布洛芬杂质5(酮基布洛芬杂质E); RAC酮洛芬酰胺; 酮洛芬酰胺
• 英文别名: Ketoprofen amide; 3-Benzoyl-|A-methylbenzeneacetamide; 2-(3-Benzoylphenyl)propanamide (Ketoprofen Impurity); Ketoprofen Impurity 5(Ketoprofen Impurity E); rac Ketoprofen AMide; (2RS)-2-(3-Benzoylphenyl)propanamid; 3-Benzoyl-α-MethylbenzeneacetaMide; 2-(3-Benzoylphenyl)propionamide; Ketoprofen Impurity E (Ketoprofen Amide); Benzeneacetamide, 3-benzoyl-α-methyl; rac Ketoprofen Amide; (RS)-2-(3-benzoylphenyl)propanamide; ketoprofen amide; Propionamide,2-(3-benzoylphenyl); ketoprofen impurity E 2-(3-benzoylphenyl)propanamide; 3-Benzoyl-alpha-methylbenzeneacetamide; Ketoprofen impurity 5/Ketoprofen Impurity E/2-(3-benzoylphenyl)propanamide

物化性质

• 密度: 1.159g/cm3
• 沸点: 469.3ºC at 760 mmHg
• 分子式: C₁₆H₁₅NO₂
• 分子量: 253.29600
• 闪点: 237.6ºC
• 精确质量: 253.11000
• PSA: 61.15000
• LogP: 3.65610
• 折射率: 1.59

合成路线

22071-15-4 ~% 59512-16-2

文献：Sumitomo Pharmaceuticals Company, Limited Patent: EP1201661 A1, 2002 ;

42872-30-0 ~73% 59512-16-2

文献：Garcia-Alvarez, Rocio; Diez, Josefina; Crochet, Pascale; Cadierno, Victorio Organometallics, 2011 , vol. 30, # 20 p. 5442 - 5451

59512-44-6 ~% 59512-16-2

文献：Borhade, Namdev; Pathan, Asif Rahimkhan; Halder, Somnath; Karwa, Manoj; Dhiman, Mini; Pamidiboina, Venu; Gund, Machhindra; Deshattiwar, Jagannath Janardhan; Mali, Sunil Vasantrao; Deshmukh, Nitin Janardanrao; Senthilkumar, Subrayan Palanisamy; Gaikwad, Parikshit; Tipparam, Santhosh Goud; Mudgal, Jayesh; Dutta, Milan Chandra; Burhan, Aslam Usmangani; Thakre, Gajanan; Sharma, Ankur; Deshpande, Shubhada; Desai, Dattatraya Chandrakant; Dubash, Nauzer Pervez; Jain, Arun Kumar; Sharma, Somesh; Nemmani, Kumar Venkata Subrahmanya; Satyam, Apparao Chemical and Pharmaceutical Bulletin, 2012 , vol. 60, # 4 p. 465 - 481