6543-77-7

• 常用中文名：强力霉素
• 常用英文名：4-Epidoxycycline
• CAS号：6543-77-7
• 分子式：C₂₂H₂₄N₂O₈
• 分子量：444.43500
• 相关类别： 原料药 抗生素类药物 四环素类药
• 发布时间：2018-02-28 08:00:00
• 更新时间：2026-07-02 18:26:42

名称

• 中文名: 4-环氧氯丙烷强力霉素
• 英文名: doxycyline
• 中文别名: 多西环素水合杂质C; 多西环素杂质C; 4-环氧丙环素; 盐酸强力霉素杂质C; 4-I强力霉素; 6-脱氧-4-差向土霉素; 4-差向多西环素; 4-表强力霉素; 4-表多西环素; 强力霉素一水物杂质C; 强力霉素(多西环素)杂质C; 强力霉素杂质3(强力霉素杂质C)(4-环氧丙环素); 4-差向异构 强力霉素; 盐酸多西环素杂质C(4-差向多西环素); 盐酸多西环素杂质C; 多西环素杂质7; 4-表多西环素(杂质C); 强力霉素杂质C
• 英文别名: 4-I DOXYCYCLINE DXC; (4R,4,5S,5,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-cboxamide (4-idoxycycline); Doxycycline Impurity C / 4-idoxycycline / Doxycycline Related Compound C; Doxycycline Impurity 3（Doxycycline Impurity C）; (4R,4,5S,5,6R,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecboxamide; 4-i Doxycycline; 4-i DoxycycL; doxycycline; 2-Naphthacenecboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4R,4,5S,5,6R,12aS); DOCYCYCLINE; Doxycycline Impurity 3(Doxycycline Impurity C)(4-i-Doxycycline); (4R,4,5S,5,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-cboxamide; 6-Deoxy-4-ioxytetracycline //BP; 4-i Doxycycline HydrochlorideQ: What is 4-i Doxycycline Hydrochloride Q: What is the CAS Number of 4-i Doxycycline Hydrochloride Q: What is the storage condition of 4-i Doxycycline Hydrochloride Q: What e the applications of 4-i Doxycycline Hydrochloride; 5-Hydroxy-α-6-desoxy-tetracyclin; doxocycline; Doxycycline Impurity 7; 4-i Doxycycline (Crude); Doxycycline Impurity C/4-i Doxycycline; (4S,4,5S,5,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-cboxamide(metacycline); Doxycycline hyclate Impurity C; 6-Deoxy-4-ioxytetracycline; 4-Epi Doxycycline; (4S,5S,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a

物化性质

• 熔点: >176?C (dec.)
• 分子式: C₂₂H₂₄N₂O₈
• 分子量: 444.43500
• 精确质量: 444.15300
• PSA: 181.62000
• LogP: 0.35270
• 储存条件: Amber Vial, -20°C Freezer, Under Inert Atmosphere

合成路线

564-25-0 ~% 6543-77-7

文献：Kertscher; Habermann; Pohle; Tauchert; Hennig; Eger Scientia Pharmaceutica, 1998 , vol. 66, # 4 p. 287 - 296

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