731018-54-5

• 常用中文名：N-(5-氟-2-噻唑)-氨基甲酸-1,1-二甲基乙酯
• 常用英文名：tert-Butyl (5-fluorothiazol-2-yl)carbamate
• CAS号：731018-54-5
• 分子式：C₈H₁₁FN₂O₂S
• 分子量：218.24900
• 发布时间：2018-11-26 16:28:11
• 更新时间：2025-08-25 18:04:34

名称

• 中文名: N-(5-氟-2-噻唑)-氨基甲酸-1,1-二甲基乙酯
• 英文名: tert-Butyl (5-fluorothiazol-2-yl)carbamate
• 中文别名: (5-氟-2-噻唑基)氨基甲酸叔丁酯; 叔丁基(5-氟噻唑-2-基)氨基甲酸酯; 叔-丁基 (5-氟噻唑-2-基)氨基甲酯
• 英文别名: N-(5-fluoro-2-thiazolyl)-, 1,1-diMethylethyl ester; (5-Fluoro-thiazol-2-yl)-cbaMic acid tert-butyl ester; Cbamic acid, N-(5-fluoro-2-thiazolyl)-, 1,1-dimethylethyl ester; (5-Fluoro-2-thiazolyl)cbamic acid 1,1-dimethylethyl ester; Cbamic acid, (5-fluoro-2-thiazolyl)-, 1,1-dimethylethyl ester; tert-butyl5-fluorothiazol-2-ylcbamate; tert-butyl 5-fluoro-1,3-thiazol-2-ylcbamate; tert-butyl N-(5-fluoro-1,3-thiazol-2-yl)cbamate; N-(5-Fluoro-2-thiazolyl)-cbamic acid 1,1-dimethylethyl ester; Cbamic acid, (5-fluoro-2-thiazolyl)-, 1,1-dimethylethyl ester (9CI); tert-butyl N-(5-fluoro-1,3-thiazol-2-yl)carbamate

物化性质

• 密度: 1.32g/cm3
• 分子式: C₈H₁₁FN₂O₂S
• 分子量: 218.24900
• 精确质量: 218.05300
• PSA: 79.46000
• LogP: 2.70220
• 折射率: 1.549
• 储存条件: 2-8°C，保存于惰性气体中

合成路线

302964-02-9 ~67% 731018-54-5

文献：TAKEDA SAN DIEGO, INC.; MATTSON, Matthew Patent: WO2011/115758 A1, 2011 ; Location in patent: Page/Page column 14 ;

170961-15-6 ~35% 731018-54-5

文献：Briner, Paul H.; Fyfe, Matthew C. T.; Martin, Pierre; Murray, P. John; Naud, Frederic; Procter, Martin J. Organic Process Research and Development, 2006 , vol. 10, # 2 p. 346 - 348

405939-39-1 ~% 731018-54-5

文献：Cheruvallath, Zacharia; Feng, Jun; Guntupalli, Prasuna; Gwaltney, Stephen L.; Kaldor, Stephen W.; Miura, Joanne; Sabat, Mark; Tang, Mingnam; Wolgast, Beverly Patent: US2007/213349 A1, 2007 ; Location in patent: Page/Page column 67 ; US 20070213349 A1

24424-99-5 ~% 731018-54-5

文献：TAKEDA SAN DIEGO, INC.; MATTSON, Matthew Patent: WO2011/115758 A1, 2011 ;

745078-03-9 ~% 731018-54-5

文献：TAKEDA SAN DIEGO, INC.; MATTSON, Matthew Patent: WO2011/115758 A1, 2011 ;