128075-79-6

• 常用中文名：鲁非罗尼
• 常用英文名：LUFIRONIL
• CAS号：128075-79-6
• 分子式：C₁₃H₁₉N₃O₄
• 分子量：281.30800
• 发布时间：2018-05-14 08:00:00
• 更新时间：2024-01-11 16:53:18

名称

• 中文名: 鲁非罗尼
• 英文名: 2-N,4-N-bis(2-methoxyethyl)pyridine-2,4-dicarboxamide
• 英文别名: lufironil; hoe 077

物化性质

• 密度: 1.161g/cm3
• 沸点: 543ºC at 760 mmHg
• 分子式: C₁₃H₁₉N₃O₄
• 分子量: 281.30800
• 闪点: 282.2ºC
• 精确质量: 281.13800
• PSA: 89.55000
• LogP: 0.61580
• 蒸汽压: 7.49E-12mmHg at 25°C
• 折射率: 1.52

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : US7961300 CHEMICAL NAME : 2,4-Pyridinedicarboxamide, N,N'-bis(2-methoxyethyl)- CAS REGISTRY NUMBER : 128075-79-6 LAST UPDATED : 199409 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C13-H19-N3-O4 MOLECULAR WEIGHT : 281.35 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JOHEEC Journal of Hepathology. (Elsevier Science, 655 Avenue of the Americas, New York, NY 10010) V.1- 1985- Volume(issue)/page/year: 13(Suppl 3),63,1991 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JOHEEC Journal of Hepathology. (Elsevier Science, 655 Avenue of the Americas, New York, NY 10010) V.1- 1985- Volume(issue)/page/year: 13(Suppl 3),63,1991 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JOHEEC Journal of Hepathology. (Elsevier Science, 655 Avenue of the Americas, New York, NY 10010) V.1- 1985- Volume(issue)/page/year: 13(Suppl 3),63,1991 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JOHEEC Journal of Hepathology. (Elsevier Science, 655 Avenue of the Americas, New York, NY 10010) V.1- 1985- Volume(issue)/page/year: 13(Suppl 3),63,1991 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 455 gm/kg/26W-I TOXIC EFFECTS : Liver - other changes REFERENCE : JOHEEC Journal of Hepathology. (Elsevier Science, 655 Avenue of the Americas, New York, NY 10010) V.1- 1985- Volume(issue)/page/year: 13(Suppl 3),63,1991

合成路线

499-80-9 109-85-3 ~% 128075-79-6

文献：Hoechst Aktiengesellschaft Patent: US5037839 A1, 1991 ;

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