200184-87-8

• 常用中文名：(2R,4R)-1-(叔丁氧基羰基)-4-甲氧基吡咯烷-2-羧酸
• 常用英文名：CIS-BOC-4-METHOXY-D-PROLINE
• CAS号：200184-87-8
• 分子式：C₁₁H₁₉NO₅
• 分子量：245.27200
• 发布时间：2017-11-17 08:34:52
• 更新时间：2026-08-02 20:13:33

名称

• 中文名: (2R,4R)-1-(叔丁氧基羰基)-4-甲氧基吡咯烷-2-羧酸
• 英文名: (2R,4R)-4-methoxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid
• 中文别名: (2R,4R)-1-BOC-4-甲氧基吡咯烷-2-甲酸; N-BOC-顺式-4-甲氧基-D-脯氨酸
• 英文别名: cis-1-(tert-Butoxycbonyl)-4-methoxypyrrolidine-2-cboxylic acid; (R,R)-4-methoxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester; (2R,4R)-1-(TERT-BUTOXYCBONYL)-4-METHOXYPYRROLIDINE-2-CBOXYLIC ACID; (2R,4R)-N-Boc-cis-4-methoxy-D-proline; (2R,4R)-4-methoxy-1-[(2-methylpropan-2-yl)oxycbonyl]pyrrolidine-2-cboxylic acid; (4R)-1-Boc-4-methoxy-D-proline; 1,2-Pyrrolidinedicboxylic acid, 4-methoxy-, 1-(1,1-dimethylethyl) ester, (2R,4R); (2R,4R)-4-methoxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester; (2R,4R)-1-Boc-4-methoxypyrrolidine-2-cboxylic Acid; 1-tert-butyl (2R,4R)-4-methoxy-pyrrolidine-1,2-dicarboxylate; 1-tert-butoxy (2R,4R)-4-methoxy-pyrrolidine-1,2-dicarboxylate; (2R,4R)-N-Boc-4-MeO-Pro-OH; (R,R)-4-methoxy-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid; 1-tert-butoxycarbonyl (2R,4R)-4-methoxy-pyrrolidine-1,2-dicarboxylate; (4R)-1-(tert-butoxycarbonyl)-4-methoxy-D-proline

物化性质

• 分子式: C₁₁H₁₉NO₅
• 分子量: 245.27200
• 精确质量: 245.12600
• PSA: 76.07000
• LogP: 1.03330

合成路线

200184-86-7 ~86% 200184-87-8

文献：ASTRAZENECA AB; ASTRAZENEKA UK LIMITED Patent: WO2005/26156 A1, 2005 ; Location in patent: Page/Page column 103 ; WO 2005/026156 A1

135042-12-5 74-88-4 ~95% 200184-87-8

文献：WARNER-LAMBERT COMPANY LLC Patent: WO2006/100565 A1, 2006 ; Location in patent: Page/Page column 14-15 ; WO 2006/100565 A1

135042-12-5 ~% 200184-87-8

文献：BOEHRINGER INGELHEIM INTERNATIONAL GMBH Patent: US2011/269737 A1, 2011 ; US 20110269737 A1

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