380893-73-2

• 常用中文名：(5-溴吡啶-2-基)甲基磷酸二乙酯
• 常用英文名：2-(diethylphosphonylmethyl)-5-bromopyridine
• CAS号：380893-73-2
• 分子式：C₁₀H₁₅BrNO₃P
• 分子量：308.10900
• 发布时间：2018-12-27 19:17:34
• 更新时间：2026-08-02 10:23:15

名称

• 中文名: (5-溴吡啶-2-基)甲基磷酸二乙酯
• 英文名: 2-(diethylphosphonylmethyl)-5-bromopyridine
• 中文别名: RSYY(利非司特T)-17; (5-溴-2-吡啶基)甲基]膦酸二乙酯; ((5-溴吡啶-2-基)甲基)膦酸二乙酯; P-[(5-溴-2-吡啶基)甲基]-膦; P-[(5-溴-2-吡啶基)甲基]-膦酸二乙酯; 5-溴-2-甲基磷酸二乙酯吡啶
• 英文别名: [(5-bromo-2-pyridinyl)methyl]-phosphonic acid diethyl ester; RSYY（Lifiteast)-17; Phosphonic acid,[[4-(bromomethyl)phenyl]difluoromethyl]-,diethyl ester; 2-(DIETHYLPHOSPHONYLMETHYL)-5-BROMOPYRIDINE; Diethyl P-[(5-bromo-2-pyridinyl)methyl]phosphonate; (4-bromomethylphenyl)difluoromethylphosphonic diethyl ester; 2-(3-METHYL-4-NITRO-PYRAZOL-1-YL)-PROPIONIC ACID; diethyl [(5-bromopyridin-2-yl)methyl]phosphonate; [(4-bromomethyl-phenyl)difluoromethyl]-phosphonic acid diethyl ester; Diethyl ((5-bromopyridin-2-yl)methyl)phosphonate; Diethyl [(5-Bromo-2-pyridyl)methyl]phosphonate; Phosphonic acid, P-[(5-bromo-2-pyridinyl)methyl]-, diethyl ester; 4-{(diethoxyphosphoryl)(difluoro)methyl}benzyl bromide

物化性质

• 分子式: C₁₀H₁₅BrNO₃P
• 分子量: 308.10900
• 精确质量: 306.99700
• PSA: 58.23000
• LogP: 3.61020

合成路线

168823-76-5 ~% 380893-73-2

文献：SCHERING CORPORATION; WU, George, G.; SUDHAKAR, Anantha; WANG, Tao; XIE, Ji; CHEN, Frank, Xing; POIRIER, Marc; HUANG, Mingsheng; SABESAN, Vijay; KWOK, Daw-long; CUI, Jian; YANG, Xiaojing; THIRUVENGADAM, Tiruvettipuram, K.; LIAO, Jing; ZAVIALOV, Ilia; NGUYEN, Hoa, N.; LIM, Ngiap Kie Patent: WO2006/76415 A2, 2006 ; Location in patent: Page/Page column 46-47 ; WO 2006/076415 A2

3430-13-5 ~% 380893-73-2

文献：Deng, Lisheng; Diao, Jiasheng; Chen, Pinhong; Pujari, Venugopal; Yao, Yuan; Cheng, Gang; Crick, Dean C.; Prasad, B. V. Venkataram; Song, Yongcheng Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4721 - 4734

31181-64-3 ~% 380893-73-2

文献：Deng, Lisheng; Diao, Jiasheng; Chen, Pinhong; Pujari, Venugopal; Yao, Yuan; Cheng, Gang; Crick, Dean C.; Prasad, B. V. Venkataram; Song, Yongcheng Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4721 - 4734

122-52-1 168823-76-5 ~% 380893-73-2

文献：Deng, Lisheng; Diao, Jiasheng; Chen, Pinhong; Pujari, Venugopal; Yao, Yuan; Cheng, Gang; Crick, Dean C.; Prasad, B. V. Venkataram; Song, Yongcheng Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4721 - 4734

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