18921-68-1

• 常用中文名：L-Glutamic acid,N-[4-[[(2,4-diamino-6-quinazolinyl)methyl]amino]benzoyl]-
• 常用英文名：L-Glutamic acid,N-[4-[[(2,4-diamino-6-quinazolinyl)methyl]amino]benzoyl]-
• CAS号：18921-68-1
• 分子式：C₂₁H₂₂N₆O₅
• 分子量：438.43700
• 发布时间：2017-11-09 00:06:53
• 更新时间：2025-10-27 14:10:46

名称

• 英文名: 2-[[4-[(2,4-diaminoquinazolin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
• 英文别名: Deazaminopterin; Deaza-Aminopterin; Dideaza-aminopterin; N-{4-[(2,4-diamino-quinazolin-6-ylmethyl)-amino]-benzoyl}-glutamic acid; N-[4-[[(2,4-Diaminoquinazolin-6-yl)methyl]amino]benzoyl]-L-glutamic acid; CB-3702; 5,8-Dideazaaminopterin

物化性质

• 密度: 1.508g/cm3
• 分子式: C₂₁H₂₂N₆O₅
• 分子量: 438.43700
• 精确质量: 438.16500
• PSA: 193.55000
• LogP: 3.08040
• 折射率: 1.747

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : MA1247500 CHEMICAL NAME : Glutamic acid, N-(p-(((2,4-diamino-6-quinazolinyl)methyl)amino)benzo yl)-, L- CAS REGISTRY NUMBER : 18921-68-1 LAST UPDATED : 198312 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C21-H22-N6-O5 MOLECULAR WEIGHT : 438.49 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 65 mg/kg TOXIC EFFECTS : Tumorigenic - active as anti-cancer agent REFERENCE : GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2709506 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 65 mg/kg TOXIC EFFECTS : Tumorigenic - active as anti-cancer agent REFERENCE : GWXXBX German Offenlegungsschrift Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2709506

安全

• 海关编码: 2933990090

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%