2820-55-5

• 常用中文名：(2'S)-尼古丁1-氧化物
• 常用英文名：(2'S)-Nicotine 1-Oxide
• CAS号：2820-55-5
• 分子式：C₁₀H₁₄N₂O
• 分子量：178.23100
• 发布时间：2018-06-11 13:19:46
• 更新时间：2024-01-02 13:35:53

名称

• 中文名: (2'S)-尼古丁1-氧化物
• 英文名: (2'S)-Nicotine 1-Oxide
• 英文别名: 1-chloroacetyl-L-proline; N-chloroacetyl-L-proline; nicotine N-oxide; nicotine nitrogen oxide

物化性质

• 密度: 1.15g/cm3
• 沸点: 347.9ºC at 760mmHg
• 分子式: C₁₀H₁₄N₂O
• 分子量: 178.23100
• 闪点: 164.2ºC
• 精确质量: 178.11100
• PSA: 28.70000
• LogP: 1.81970
• 蒸汽压: 5.22E-05mmHg at 25°C
• 折射率: 1.589
• 储存条件: 2-8°C， 充氩

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : QS9604000 CHEMICAL NAME : Nicotine, 1-oxide CAS REGISTRY NUMBER : 2820-55-5 LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C10-H14-N2-O HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 295 mg/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 24,534,1961 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 295 mg/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 24,534,1961 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 24100 ug/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea REFERENCE : FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 24,534,1961 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Amphibian - frog DOSE/DURATION : 750 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 11,1011,1961

安全

• 海关编码: 2933990090

合成路线

2055-29-0 ~95% 2820-55-5

文献：Kokatla, Hari Prasad; Thomson, Paul F.; Bae, Suyeal; Doddi, Venkata Ramana; Lakshman, Mahesh K. Journal of Organic Chemistry, 2011 , vol. 76, # 19 p. 7842 - 7848

2055-29-0 ~31% 2820-55-5 54-11-5

文献：Takeshita, Mitsuhiro; Yoshida, Sachiko Heterocycles, 1990 , vol. 30, # 2 p. 871 - 874

54-11-5 ~% 2820-55-5

文献：Schmidt, Boris; Neitemeier, Vera Synthesis, 1998 , # 1 p. 42 - 44

上下游产品

上游产品  2
2055-29-0 54-11-5
下游产品  5
36508-80-2 13270-56-9 77698-47-6 101540-79-8
64114-31-4

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%