58802-08-7

• 常用中文名：1,2,4,7,8-五氯二苯并-对-二恶英
• 常用英文名：1,2,4,7,8-Pentachlorodibenzo-p-dioxin
• CAS号：58802-08-7
• 分子式：C₁₂H₃Cl₅O₂
• 分子量：356.41600
• 发布时间：2018-12-03 17:07:53
• 更新时间：2024-01-08 07:26:01

名称

• 中文名: 1,2,4,7,8-五氯二苯并-对-二恶英
• 英文名: 1,2,4,7,8-Pentachlorodibenzo-p-dioxin
• 中文别名: 1,2,4,7,8-五氯二苯并对二噁英; 1,2,4,7,8-五氯二苯并-对-二噁英
• 英文别名: Dibenzo-p-dioxin,1,2,4,7,8-pentachloro; 1,2,4,7,8-P5CDD; 1,2,4,7,8-pentachlorodibenzodioxin; 1,2,4,7,8-PCDD; 1,2,4,7,8-pentachlorooxanthrene

物化性质

• 密度: 1.714g/cm3
• 沸点: 443.9ºC at 760mmHg
• 分子式: C₁₂H₃Cl₅O₂
• 分子量: 356.41600
• 闪点: 171.7ºC
• 精确质量: 353.85800
• PSA: 18.46000
• LogP: 6.85160
• 折射率: 1.661

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : HP3420000 CHEMICAL NAME : Dibenzo-p-dioxin, 1,2,4,7,8-pentachloro- CAS REGISTRY NUMBER : 58802-08-7 BEILSTEIN REFERENCE NO. : 1627438 LAST UPDATED : 199710 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C12-H3-Cl5-O2 MOLECULAR WEIGHT : 356.40 WISWESSER LINE NOTATION : T C666 BO IOJ DG EG GG LG MG HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >5 mg/kg TOXIC EFFECTS : Endocrine - changes in spleen weight Endocrine - changes in thymus weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 44,335,1978 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 1125 ug/kg TOXIC EFFECTS : Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 44,335,1978 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,41,1977 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

合成路线

39227-28-6 ~% 34816-53-0 40321-76-4 58802-08-7 详细

文献：Addink, Ruud; Antonioli, Mischa; Olie, Kees; Covers, Harrie A. J. Environmental Science and Technology, 1996 , vol. 30, # 3 p. 833 - 836

35471-43-3 58200-75-2 ~% 58802-08-7

文献：Buser, Hans Rudolf; Rappe, Christoffer Analytical Chemistry, 1984 , vol. 56, # 3 p. 442 - 448

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