197904-84-0
197904-84-0结构式
- 常用中文名：CS701
- 常用英文名：CS701
- CAS号：197904-84-0
- 分子式：C19H20N2O3S
- 分子量：356.43900
- 发布时间：2016-06-08 14:41:57
- 更新时间：2025-09-19 20:13:51
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Apricoxib, also known as Benzenesulfonamide 42(4ethoxyphenyl)4methyl1Hpyrrol1yl, is an orally bioavailable nonsteroidal anti-inflammatory agent (NSAID) with potential antiangiogenic and antineoplastic activities. Apricoxib binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), thereby inhibiting the conversion of arachidonic acid into prostaglandins. Apricoxib-mediated inhibition of COX-2 may induce tumor cell apoptosis and inhibit tumor cell proliferation and tumor angiogenesis. COX-related metabolic pathways may represent crucial regulators of cellular proliferation and angiogenesis.
| 英文名 | 4-[2-(4-ethoxyphenyl)-4-methylpyrrol-1-yl]benzenesulfonamide |
|---|---|
| 英文别名 |
UNII-5X5HB3VZ3Z
TG01 Kymena Capoxigem CS-706 Apricoxib |
| 密度 | 1.249 g/cm3 |
|---|---|
| 沸点 | 555.289ºC at 760 mmHg |
| 分子式 | C19H20N2O3S |
| 分子量 | 356.43900 |
| 闪点 | 289.628ºC |
| 精确质量 | 356.11900 |
| PSA | 82.70000 |
| LogP | 5.27990 |