89797-00-2

• 常用中文名：碘喷托
• 常用英文名：Iopentol
• CAS号：89797-00-2
• 分子式：C₂₀H₂₈I₃N₃O₉
• 分子量：835.16
• 相关类别： 研究领域 其他
• 发布时间：2018-03-18 08:00:00
• 更新时间：2024-01-06 11:53:07
• Iopentol是一种非离子型血管内造影剂[1]。

名称

• 中文名: 碘喷托
• 英文名: 5-[acetyl-(2-hydroxy-3-methoxypropyl)amino]-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide
• 英文别名: IOPENTOL; UNII-7D6XWX076T; Iopentolum; Imagopaque

物化性质

• 密度: 2.095g/cm3
• 沸点: 858.8ºC at 760 mmHg
• 分子式: C₂₀H₂₈I₃N₃O₉
• 分子量: 835.16
• 闪点: 473.2ºC
• 精确质量: 834.89600
• PSA: 195.87000
• LogP: 0.17620
• 折射率: 1.693
• 储存条件: -20°C，密闭，干燥

生物活性

• 描述: Iopentol是一种非离子型血管内造影剂[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Aulie Michelet A. Effects of intravascular contrast media on blood-brain barrier. Comparison between iothalamate, iohexol, iopentol and iodixanol. Acta Radiol. 1987 May-Jun;28(3):329-33.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CZ2211000 CHEMICAL NAME : 1,3-Benzenedicarboxamide, 5-(acetyl(2-hydroxy-3-methoxypropyl)amino)-N,N'-bis (2,3-dihydroxypropyl)-2,4,6-triiodo- CAS REGISTRY NUMBER : 89797-00-2 LAST UPDATED : 199509 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C20-H28-I3-N3-O9 MOLECULAR WEIGHT : 835.21 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 22573 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARASA5 Acta Radiologica, Supplementum. (Acta Radiologica, POB 7449, S-10391 Stockholm, Sweden) No.1- 1921- Volume(issue)/page/year: 370,41,1987 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 42517 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARASA5 Acta Radiologica, Supplementum. (Acta Radiologica, POB 7449, S-10391 Stockholm, Sweden) No.1- 1921- Volume(issue)/page/year: 370,41,1987 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Primate - monkey DOSE/DURATION : 553 gm/kg/28D-I TOXIC EFFECTS : Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Endocrine - changes in thyroid weight REFERENCE : ARASA5 Acta Radiologica, Supplementum. (Acta Radiologica, POB 7449, S-10391 Stockholm, Sweden) No.1- 1921- Volume(issue)/page/year: 370,45,1987

安全

• 危险品运输编码: NONH for all modes of transport