164455-27-0

• 常用中文名：N-Deethyl Dorzolamide Hydrochloride
• 常用英文名：N-Deethyl Dorzolamide Hydrochloride
• CAS号：164455-27-0
• 分子式：C₈H₁₃ClN₂O₄S₃
• 分子量：332.84800
• 发布时间：2017-09-07 10:46:01
• 更新时间：2025-08-25 20:18:22

名称

• 英文名: (4S,6S)-4-amino-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide,hydrochloride
• 英文别名: 4H-Thieno(2,3-b)thiopyran-2-sulfonamide,5,6-dihydro-4-amino-6-methyl-,7,7-dioxide,monohydrochloride,(4S-trans); (4S,6S)-4-amino-6-methyl-7,7-dioxo-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide hydrochloride; UNII-P7DT2GS6VD; N-Deethyldorzolamide hydrochloride

物化性质

• 沸点: 584.3ºC at 760 mmHg
• 分子式: C₈H₁₃ClN₂O₄S₃
• 分子量: 332.84800
• 闪点: 307.2ºC
• 精确质量: 331.97300
• PSA: 165.32000
• LogP: 4.32540
• 蒸汽压: 1.22E-13mmHg at 25°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : XJ9095113 CHEMICAL NAME : 4H-Thieno(2,3-b)thiopyran-2-sulfonamide, 5,6-dihydro-4-amino-6-methyl-, 7,7-dioxide, monohydrochloride, (4S-trans)- CAS REGISTRY NUMBER : 164455-27-0 LAST UPDATED : 199601 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C8-H12-N2-O4-S3.Cl-H HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >800 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea REFERENCE : KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 28,1241,1994