112111-44-1

• 常用中文名：(S)-(+)-莫达芬酸
• 常用英文名：(S)-(+)-Modafinic acid
• CAS号：112111-44-1
• 分子式：C₁₅H₁₄O₃S
• 分子量：274.33500
• 发布时间：2017-05-13 04:03:51
• 更新时间：2026-08-24 21:35:10

名称

• 中文名: (S)-(+)-莫达芬酸
• 英文名: 2-[(S)-benzhydrylsulfinyl]acetic acid
• 中文别名: [(S)-(二苯基甲基)亚磺酰基]乙酸
• 英文别名: (S)-(+)-modafinic acid; Acetic acid,2-[(S)-(diphenylmethyl)sulfinyl]; Acetic acid, 2-[(S)-(diphenylmethyl)sulfinyl]; Modafinil Acid S-Isomer; (S)-((addition))-Modafinic acid; [(S)-(Diphenylmethyl)sulfinyl]acetic acid; (+)-(S)-(diphenylmethanesulfinyl)acetic acid; modafinil Impurity 5/2-[(S)-(Diphenylmethyl) sulfinyl]acetic Acid; Acetic acid,[(S)-(diphenylmethyl)sulfinyl]; ACE044; modafinic acid; S-(+)-2-(benzhydrylsulfinyl)acetic acid; Pinacolborane Impurity 13; 2-(benzhydryl S-sulfinyl)acetic acid; Acetic acid, [(S)-(diphenylMethyl)sulfinyl]; 2-[(S)-(Diphenylmethyl)sulfinyl]acetic acid; (S)-(+)-(benzhydrylsulfinyl)-acetic acid

物化性质

• 分子式: C₁₅H₁₄O₃S
• 分子量: 274.33500
• 精确质量: 274.06600
• PSA: 73.58000
• LogP: 3.47500

合成路线

63547-22-8 ~% 112111-45-2 112111-44-1

文献：EMCURE PHARMACEUTICALS LIMITED Patent: WO2008/152462 A1, 2008 ; Location in patent: Page/Page column 13 ;

827603-88-3 ~89% 112111-44-1

文献：Osorio-Lozada, Antonio; Prisinzano, Thomas; Olivo, Horacio F. Tetrahedron Asymmetry, 2004 , vol. 15, # 23 p. 3811 - 3815

63547-22-8 ~88% 112111-44-1

文献：Olivo, Horacio F.; Osorio-Lozada, Antonio; Peeples, Tonya L. Tetrahedron Asymmetry, 2005 , vol. 16, # 21 p. 3507 - 3511

112111-45-2 ~% 112111-44-1

文献：TEVA PHARMACEUTICAL INDUSTRIES LTD.; TEVA PHARMACEUTICALS USA, INC. Patent: WO2008/70143 A1, 2008 ; Location in patent: Page/Page column 9 ;

91-01-0 ~% 112111-44-1

文献：Prisinzano, Thomas; Podobinski, John; Tidgewell, Kevin; Luo, Min; Swenson, Dale Tetrahedron Asymmetry, 2004 , vol. 15, # 6 p. 1053 - 1058

63547-24-0 ~% 112111-45-2 112111-44-1

文献：Prisinzano, Thomas; Podobinski, John; Tidgewell, Kevin; Luo, Min; Swenson, Dale Tetrahedron Asymmetry, 2004 , vol. 15, # 6 p. 1053 - 1058

63547-24-0 ~% 112111-44-1

文献：Osorio-Lozada, Antonio; Prisinzano, Thomas; Olivo, Horacio F. Tetrahedron Asymmetry, 2004 , vol. 15, # 23 p. 3811 - 3815

63547-23-9 ~% 112111-44-1

文献：Prisinzano, Thomas; Podobinski, John; Tidgewell, Kevin; Luo, Min; Swenson, Dale Tetrahedron Asymmetry, 2004 , vol. 15, # 6 p. 1053 - 1058

118286-19-4 ~% 112111-44-1

文献：Prisinzano, Thomas; Podobinski, John; Tidgewell, Kevin; Luo, Min; Swenson, Dale Tetrahedron Asymmetry, 2004 , vol. 15, # 6 p. 1053 - 1058

上下游产品

上游产品  7
63547-22-8 827603-88-3 112111-45-2 91-01-0
63547-24-0 63547-23-9 118286-19-4
下游产品  3
865811-65-0 63547-22-8 112111-45-2