851224-80-1

• 常用中文名：ethyl 3-(4-(trifluoromethyl)phenyl)-1,2,4-thiadiazole-5-carboxylate
• 常用英文名：ethyl 3-(4-(trifluoromethyl)phenyl)-1,2,4-thiadiazole-5-carboxylate
• CAS号：851224-80-1
• 分子式：C₁₂H₉F₃N₂O₂S
• 分子量：302.27200
• 发布时间：2016-09-07 12:59:24
• 更新时间：2024-01-09 15:52:54

名称

• 英文名: ethyl 3-[4-(trifluoromethyl)phenyl]-1,2,4-thiadiazole-5-carboxyla te
• 英文别名: 3-(4-trifluoromethylphenyl)[1,2,4]thiadiazole-5-carboxylic acid ethyl ester; Pyrrolidine,3-[4-(trifluoromethyl)phenoxy]; 3-(4-trifluoromethyl-phenoxy)-pyrrolidine

物化性质

• 分子式: C₁₂H₉F₃N₂O₂S
• 分子量: 302.27200
• 精确质量: 302.03400
• PSA: 80.32000
• LogP: 3.40060

合成路线

851224-79-8 623-49-4 ~90% 851224-80-1

文献：Kuo, Gee-Hong; Zhang, Yan; Shen, Lan; Lu, Songfeng; Demarest, Keith T.; Peiton, Patricia Patent: US2007/244094 A1, 2007 ; Location in patent: Page/Page column 25 ;

1891-90-3 ~% 851224-80-1

文献：Shen, Lan; Zhang, Yan; Wang, Aihua; Sieber-McMaster, Ellen; Chen, Xiaoli; Pelton, Patricia; Xu, Jun Z.; Yang, Maria; Zhu, Peifang; Zhou, Lubing; Reuman, Michael; Hu, Zhiyong; Russell, Ronald; Gibbs, Alan C.; Ross, Hamish; Demarest, Keith; Murray, William V.; Kuo, Gee-Hong Journal of Medicinal Chemistry, 2007 , vol. 50, # 16 p. 3954 - 3963