99532-53-3

• 常用中文名：1-(5-氟-3-吲哚基)乙酮
• 常用英文名：1-(5-Fluoro-1H-indol-3-yl)ethanone
• CAS号：99532-53-3
• 分子式：C₁₀H₈FNO
• 分子量：177.17500
• 发布时间：2017-08-07 05:04:00
• 更新时间：2026-09-07 20:13:04

名称

• 中文名: 1-(5-氟-3-吲哚基)乙酮
• 英文名: 1-(5-Fluoro-1H-indol-3-yl)ethanone
• 中文别名: 1-(5-氟-1H-吲哚-3-基)乙酮
• 英文别名: 1-(5-Fluoro-3-indolyl)ethanone; Ethanone, 1-(5-fluoro-1H-indol-3-yl); Nicotinic acid,5-acetyl-1,4-dihydro-2,6-dimethyl-4-phenyl-,ethyl ester; 5-Acetyl-2,6-dimethyl-4-phenyl-1,4-dihydro-pyridin-3-carbonsaeure-aethylester; 3-acetyl-5-ethoxycarbonyl-2,6-dimethyl-4-phenyl-1,4-dihydropyridine; 2,6-Dimethyl-4-phenyl-5-acetyl-1,4-dihydropyridine-3-carboxylic acid ethyl ester; 3-acetyl-5-fluoro-1H-indole; 3-acetyl-5-fluoroindole; Ethyl 5-acetyl-2,6-dimethyl-4-phenyl-1,4-dihydro-3-pyridinecarboxylate; 4-phenyl-2,6-dimethyl-3-aceto-1,4-dihydropyridine-5-carboxylic acid ethyl ester; 5-acetyl-2,6-dimethyl-4-phenyl-1,4-dihydro-pyridine-3-carboxylic acid ethyl ester; 2,6-Dimethyl-3-ethoxycarbonyl-4-phenyl-5-acetyl-1,4-dihydro-pyridin; 1-(5-fluoro-1H-indol-3-yl)ethanone; 5-fluoro-3-acetylindole

物化性质

• 分子式: C₁₀H₈FNO
• 分子量: 177.17500
• 精确质量: 177.05900
• PSA: 32.86000
• LogP: 2.50960

合成路线

399-52-0 108-24-7 ~74% 99532-53-3

文献：Pais, Godwin C. G.; Zhang, Xuechun; Marchand, Christophe; Neamati, Nouri; Cowansage, Kiriana; Svarovskaia, Evguenia S.; Pathak, Vinay K.; Tang, Yun; Nicklaus, Marc; Pommier, Yves; Burke Jr., Terrence R. Journal of Medicinal Chemistry, 2002 , vol. 45, # 15 p. 3184 - 3194

399-52-0 127-19-5 ~45% 99532-53-3

文献：Ferro, Stefania; De Luca, Laura; Lo Surdo, Giuseppa; Morreale, Francesca; Christ, Frauke; Debyser, Zeger; Gitto, Rosaria; Chimirri, Alba Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 7 p. 2269 - 2279

99532-44-2 ~% 99532-53-3

文献：Ketcha, Daniel M.; Gribble, Gordon W. Journal of Organic Chemistry, 1985 , vol. 50, # 26 p. 5451 - 5457

348-36-7 ~% 99532-53-3

文献：Zhang, Fan; Zhao, Yanfang; Sun, Li; Ding, Lu; Gu, Yucheng; Gong, Ping European Journal of Medicinal Chemistry, 2011 , vol. 46, # 7 p. 3149 - 3157

823-85-8 ~% 99532-53-3

文献：Zhang, Fan; Zhao, Yanfang; Sun, Li; Ding, Lu; Gu, Yucheng; Gong, Ping European Journal of Medicinal Chemistry, 2011 , vol. 46, # 7 p. 3149 - 3157

371-40-4 ~% 99532-53-3

文献：Zhang, Fan; Zhao, Yanfang; Sun, Li; Ding, Lu; Gu, Yucheng; Gong, Ping European Journal of Medicinal Chemistry, 2011 , vol. 46, # 7 p. 3149 - 3157

399-76-8 ~% 99532-53-3

文献：Zhang, Fan; Zhao, Yanfang; Sun, Li; Ding, Lu; Gu, Yucheng; Gong, Ping European Journal of Medicinal Chemistry, 2011 , vol. 46, # 7 p. 3149 - 3157