108436-36-8

• 常用中文名：2'-单脱羟基-2'-氯更昔洛韦
• 常用英文名：2'-Monodehydroxy-2'-chloro Ganciclovir
• CAS号：108436-36-8
• 分子式：C₉H₁₂ClN₅O₃
• 分子量：273.67600
• 发布时间：2016-11-09 14:41:43
• 更新时间：2026-08-08 11:01:55

名称

• 中文名: 2'-单脱羟基-2'-氯更昔洛韦
• 英文名: 2-amino-9-[(1-chloro-3-hydroxypropan-2-yl)oxymethyl]-3H-purin-6-one
• 中文别名: 更昔洛韦杂质C(更昔诺韦杂质); 更昔洛韦杂质; 更昔洛韦杂质3(更昔洛韦杂质C); 2'-去羟基-2'-氯更昔洛韦; 更昔洛韦杂质03; 更昔洛韦杂质C
• 英文别名: Valganciclovir Imp.I : 2-Amino-9-[[[(2RS)-1-chloro-3-hydroxypropan-2-yl]oxy]methyl]-1,9-dihydro-6H-purin-6-one; 6H-Purin-6-one, 2-amino-9-[[2-chloro-1-(hydroxymethyl)ethoxy]methyl]-1,9-dihydro; Ganciclovir impurity C; Ganciclovir Impurity 3（ Impurity C）; Ganciclovir Impurity 3; 2-Amino-9-[[(1RS)-2-chloro-1-(hydroxymethyl)ethoxy]methyl]-1,9-dihydro-6H-purin-6-one (Monochloroganciclovir); Ganciclovir impurities816; Ganciclovir Impurity 3(Ganciclovir Impurity C); 2-amino-9-(((1-chloro-3-hydroxypropan-2-yl)oxy)methyl)-1,9-dihydro-6H-purin-6-one; 2-Amino-9-[[(1RS)-2-chloro-1-(hydroxymethyl)ethoxy]methyl]-1,9-dihydro-6H-purin-6-one (Monochlorogan; Gancyclovir Impurity 7; 2`-Monodehydroxy-2`-chloro Ganciclovir; Valganciclovir Monochloro Ganciclovir Impurity; Ganciclovir Impurity C (Ganciclovir Impurity）

物化性质

• 分子式: C₉H₁₂ClN₅O₃
• 分子量: 273.67600
• 精确质量: 273.06300
• PSA: 120.04000

合成路线

103024-99-3 ~% 108436-36-8

文献：Martin; McGee; Jeffrey; Hobbs; Smee; Matthews; Verheyden Journal of Medicinal Chemistry, 1986 , vol. 29, # 8 p. 1384 - 1389

73-40-5 ~% 108436-36-8

文献：Zakerinia; Davary; Hakimelahi Helvetica Chimica Acta, 1990 , vol. 73, # 4 p. 912 - 915

上下游产品

上游产品  1
73-40-5
下游产品  0