174819-21-7

• 常用中文名：N-苄基戊二烯
• 常用英文名：SE 563
• CAS号：174819-21-7
• 分子式：C₂₂H₁₇ClF₃NO₃
• 分子量：435.82300
• 发布时间：2017-07-30 19:41:12
• 更新时间：2025-11-28 18:19:01

名称

• 中文名: N-苄基戊二烯
• 英文名: (4S)-6-chloro-4-(2-cyclopropylethynyl)-1-[(4-methoxyphenyl)methyl]-4-(trifluoromethyl)-3,1-benzoxazin-2-one
• 中文别名: 依法韦仑杂质4(依法韦仑IP杂质D)
• 英文别名: unii-bb295u888k; (4S)-6-Chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-1-[(4-methoxyphenyl)methyl]-4-(trifluoromethyl)-2H-3,1-benzoxazin-2-one; (S)-6-Chloro-4-(cyclopropylethynyl)-1-(4-methoxybenzyl)-4-(trifluoromethyl)-1,4-dihydro-2H-benzo[d][; Efavirenz Impurity 15; 2H-3,1-Benzoxazin-2-one, 6-chloro-4-(2-cyclopropylethynyl)-1,4-dihydro-1-[(4-methoxyphenyl)methyl]-4-(trifluoromethyl)-, (4S); Efavirenz N-Methoxybenzyl Impurity

物化性质

• 分子式: C₂₂H₁₇ClF₃NO₃
• 分子量: 435.82300
• 精确质量: 435.08500
• PSA: 38.77000
• LogP: 5.74140

合成路线

75-44-5 173676-60-3 ~94% 174819-21-7

文献：Thompson, Andrew S.; Corley, Edward G.; Huntington, Martha F.; Grabowski, E. J. J. Tetrahedron Letters, 1995 , vol. 36, # 49 p. 8937 - 8940

154598-53-5 ~% 174819-21-7

文献：Thompson, Andrew S.; Corley, Edward G.; Huntington, Martha F.; Grabowski, E. J. J. Tetrahedron Letters, 1995 , vol. 36, # 49 p. 8937 - 8940

173676-54-5 ~% 174819-21-7

文献：Thompson, Andrew S.; Corley, Edward G.; Huntington, Martha F.; Grabowski, E. J. J. Tetrahedron Letters, 1995 , vol. 36, # 49 p. 8937 - 8940

105-13-5 ~% 174819-21-7

文献：Pierce, Michael E.; Parsons Jr., Rodney L.; Radesca, Lilian A.; Lo, Young S.; Silverman, Stuart; Moore, James R.; Islam, Qamrul; Choudhury, Anusuya; Fortunak, Joseph M. D.; Nguyen, Dieu; Luo, Chi; Morgan, Susan J.; Davis, Wayne P.; Confalone, Pat N.; Chen, Cheng-Yi; Tillyer, Richard D.; Frey, Lisa; Tan, Lushi; Xu, Feng; Zhao, Dalian; Thompson, Andrew S.; Corley, Edward G.; Grabowski, Edward J. J.; Reamer, Robert; Reider, Paul J. Journal of Organic Chemistry, 1998 , vol. 63, # 23 p. 8536 - 8543

65854-91-3 ~% 174819-21-7

文献：Thompson, Andrew S.; Corley, Edward G.; Huntington, Martha F.; Grabowski, E. J. J. Tetrahedron Letters, 1995 , vol. 36, # 49 p. 8937 - 8940