1345413-20-8

• 常用中文名：(1S,2R)-2-(3,4-二氟苯基)-环丙胺
• 常用英文名：(1S,2R)-2-(3,4-Difluorophenyl)-cyclopropanaMine
• CAS号：1345413-20-8
• 分子式：C₉H₉F₂N
• 分子量：169.171
• 发布时间：2018-03-24 08:00:00
• 更新时间：2026-08-14 12:47:12

名称

• 中文名: 替卡格雷-int A
• 英文名: trans-(1S,2R)-2-(3,4-difluorophenyl)-cyclopropylamine
• 中文别名: 替卡格雷杂质10; 替格瑞洛SM3杂质T; 替格瑞洛杂质盐酸盐; (1S,2R)-2-(3,4-二氟苯)-环丙胺; 替格瑞洛杂质A(单体); 替格瑞洛杂质A-12; 替卡格雷相关化合物VIII; (1S,2R)-2-(3,4-二氟苯基)环丙胺(S)-2-羟基-2-苯基乙酸酯; 替格瑞洛中间体2; 替格瑞洛相关化合物VIII; 替格瑞洛相关化合物6盐酸盐; 替卡格雷杂质; (1S,2R)-2-(3,4-二氟苯基)环丙胺(S)-2-羟基-2-苯基乙酸酯(替格瑞洛杂质); 替格瑞洛杂质14单体; 反式-(1S,2R)-2-(3,4-二氟苯基)-环丙基胺; 替卡格雷-INT A; 替卡格雷相关化合物III; 替格瑞洛侧链异构体1 盐酸盐
• 英文别名: cis-2-(3,4-difluorophenyl) cyclopropanamine (1S,2R)-2-(3,4-difluorophenyl)cyclopropanamine; (1S,2R)-2-(3,4-Difluorophenyl)cyclopropan-1-amine; Abacavir Impurity 25; (1S,2R)-2-(3,4-Difluorophenyl)cyclopropanamine; (1S,2R)-2-(3,4-difluorophenyl)cyclopropanamine (S)-2-hydroxy-2-phenylacetate (Ticaelor Impurity）; (1S,2R)-2-(3,4-difluorophenyl); Ticaelor SM3 Impurity T; Ticaelor Impurity 23 Mandelate; Cyclopropanamine, 2-(3,4-difluorophenyl)-, (1S,2R); (1S,2R)-2-(3,4-DIFLUOROPHENYL)-CYCLOPROPANAMINE; (1S,2R)-2-(3,4-Difluoro-phenyl)-cyclopropylamine; (1S,2R)-2-(3,4-difluorophenyl) cyclopropanamine; Ticaelor Related Compound VIII; ((1S,2R)-2-(3,4-Difluorophenyl)cyclopropanamine HCl)

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 212.5±40.0 °C at 760 mmHg
• 分子式: C₉H₉F₂N
• 分子量: 169.171
• 闪点: 99.0±14.4 °C
• 精确质量: 169.070313
• PSA: 26.02000
• LogP: 1.27
• 蒸汽压: 0.2±0.4 mmHg at 25°C
• 折射率: 1.539

合成路线

1215969-79-1 ~% 1345413-20-8

文献：ACTAVIS GROUP PTC EHF; KHILE, Anil, Shahaji; PATEL, Jayesh; TRIVEDI, Nikhil; PRADHAN, Nitin, Sharadchandra Patent:   WO2011/132083 A2, 2011 ;

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