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上海化源世纪贸易有限公司
上海市上海市普陀区
产品名：烯丙基雌烯醇
纯度：98.0%
规格：
联系人：徐经理
联系电话：13311869306

上海吉至生化科技有限公司
上海市上海市奉贤区
产品名：烯丙基雌烯醇
纯度：98.0%
规格：1g
联系人：刘佳
联系电话：18116092098

上海阿拉丁生化科技股份有限公司
上海市上海市浦东新区
产品名：烯丙基雌烯醇
纯度：98.0%
规格：1g/250mg/5g/1ml
联系人：阿拉丁
联系电话：400-620-6333

上海创赛科技有限公司
上海市上海市嘉定区
产品名：[Perfemiker]烯丙基雌烯醇,98%
纯度：98.0%
规格：250mg/1g
联系人：夏言
联系电话：18016376636

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432-60-0生产厂家

432-60-0

432-60-0结构式

常用中文名：烯丙基雌烯醇
常用英文名：Allylestrenol
CAS号：432-60-0
分子式：C₂₁H₃₂O
分子量：300.478
相关类别：原料药激素及调节内分泌功能类药雌激素及孕激素类药
发布时间：2018-09-22 13:22:15
更新时间：2024-01-02 18:07:05
Allylestrenol 是一种合成的性类固醇,在世界范围内用于濒危怀孕。

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中文名	烯丙基雌烯醇
英文名	Allylestrenol
中文别名	烯丙基雌醇烯丙雌醇
英文别名	allyloestrenol 17α-Allyl-4-oestrene-17β-ol EINECS 207-082-9 organon allyl-estreno 17-Allylestr-4-en-17b-ol Estr-4-en-17β-ol, 17-allyl- Estr-4-en-17-ol, 17-(2-propen-1-yl)-, (17β)- (8R,9S,10R,13S,14S,17R)-17-Allyl-13-methyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol 17α-Allylestr-4-en-17β-ol MFCD00198957 17-Hydroxy-17a-allyl-4-estrene (17β)-17-(prop-2-en-1-yl)estr-4-en-17-ol Estr-4-en-17-ol, 17-(2-propenyl)-, (17β)- Estr-4-en-17-ol, 17- (2-propenyl)-, (17β)- 17α-Allyl-17β-hydroxy-4-estrene Gestanin (17β)-17-prop-2-en-1-ylestr-4-en-17-ol 17a-Allyl-17-hydroxy-19-nor-4-androstene Turinal allylestrenol Orageston 17α-Allyl-4-estren-17β-ol Gestanon gestanyn Gestanol

描述	Allylestrenol 是一种合成的性类固醇,在世界范围内用于濒危怀孕。
相关类别	研究领域 >> 内分泌信号通路 >> 其他 >> 其他
参考文献	[1]. Pap E, et al. Effect of prenatal allylestrenol treatment (hormonal imprinting) on the serum testosterone and progesterone level in adult rats. Gen Pharmacol. 1995 Mar;26(2):365-7.

密度	1.0±0.1 g/cm3
沸点	405.4±44.0 °C at 760 mmHg
熔点	78 - 81ºC
分子式	C₂₁H₃₂O
分子量	300.478
闪点	170.6±20.7 °C
精确质量	300.245331
PSA	20.23000
LogP	6.64
外观性状	白色结晶粉末
蒸汽压	0.0±2.1 mmHg at 25°C
折射率	1.553
储存条件	库房通风低温干燥,与食品原料分开存放

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KG7960000

CHEMICAL NAME :: Estr-4-en-17-beta-ol, 17-allyl-

CAS REGISTRY NUMBER :: 432-60-0

BEILSTEIN REFERENCE NO. :: 3148038

LAST UPDATED :: 199612

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C21-H32-O

MOLECULAR WEIGHT :: 300.53

WISWESSER LINE NOTATION :: L E5 B666 MUTJ E1 FQ F2U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >640 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,41,1982 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 8 mg/kg

SEX/DURATION :: female 20 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - other measures of fertility

REFERENCE :: INJFA3 International Journal of Fertility. (Allen Press, 1041 New Hampshire, St., Lawrence, KS 66044) V.1- 1955- Volume(issue)/page/year: 9,57,1964

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 900 mg/kg

SEX/DURATION :: female 13-21 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - urogenital system

REFERENCE :: ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 65,29,1970

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 300 mg/kg

SEX/DURATION :: male 15 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct

REFERENCE :: IJMRAQ Indian Journal of Medical Research. (Indian Council of Medical Research, Ansari Nagar, New Delhi 110 029, India) V.1- 1913- Volume(issue)/page/year: 59,768,1971

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 15 mg/kg

SEX/DURATION :: male 15 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands

REFERENCE :: IJMRAQ Indian Journal of Medical Research. (Indian Council of Medical Research, Ansari Nagar, New Delhi 110 029, India) V.1- 1913- Volume(issue)/page/year: 59,768,1971

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 175 mg/kg

SEX/DURATION :: female 15-21 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - urogenital system

REFERENCE :: ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 38,128,1961

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 900 mg/kg

SEX/DURATION :: female 13-21 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - urogenital system

REFERENCE :: ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 65,29,1970

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

DOSE :: 2100 ug/kg

SEX/DURATION :: female 15-19 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - behavioral

REFERENCE :: JDPHDH Journal of Developmental Physiology. (Oxford University Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1979- Volume(issue)/page/year: 19,67,1993

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

DOSE :: 4500 ug/kg

SEX/DURATION :: female 15-19 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Newborn - biochemical and metabolic

REFERENCE :: GEPHDP General Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.6- 1975- Volume(issue)/page/year: 26,365,1995

3052-45-7结构式

3052-45-7

~%

432-60-0结构式

432-60-0

文献：de Winter et al. Chemistry and Industry (London, United Kingdom), 1959 , p. 905

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